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PRF

Written by Lenka Chodáková on . Posted in PRF.

How to apply

How to apply

e-application

Part of the e-application is:

  • Curriculum vitae
  • Motivation letter - introduce yourself; explain your motivation and interest in the study programme, and your previous research experience.

  • A proof of English language proficiency * - certificates at CEFR B2 level and higher or an official computer-based TOEFL test score of 180 or higher, or a paper-based TOEFL test score of 500 or higher. The proof is not needed if you passed the final Bachelor's exam in English at the Faculty of Science of the University of South Bohemia with a grade better than or equal to "very good minus" or if you come from a country where English is the main language, that is Australia, anglophone Canada, Ireland, New Zealand, United Kingdom, United States of America, South Africa.

  • A certified copy of the Bachelor’s degree * needs to be submitted by 13 June 2024. 

     * applicants may request documents to be submitted at a later date by emailing the Department of Student Affairs (This email address is being protected from spambots. You need JavaScript enabled to view it.).

 

Please also check the General Information for prospective students, for additional information please contact Department of Student Affairs.

Certification of Bachelor's degree

You need to submit a certified hardcopy of your Bachelor's diploma that will be recognized by our Vice-dean for Bachelor and Master Studies. The types of diplomas/certificates and legal requirements differ widely between countries. It is therefore recommended to send the Department of Student Affairs (This email address is being protected from spambots. You need JavaScript enabled to view it.) a scan of your documents for pre-checking. The Department will inform you about any further requirements. There are various levels of document authentication and translation to Czech or English may be required in some cases.

International administration - visa

Depending on your nationality and status, you might have to apply for a visa or residence permit to enter and study in the Czech Republic. You should start your visa application as soon as possible as the whole procedure can take several months. Information about visas are available on our website at https://www.jcu.cz/study-at-usb/practical-info/immigration-visa-information

Contact the Department of Student Affairs (This email address is being protected from spambots. You need JavaScript enabled to view it.) for assistence.

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Written by Lenka Chodáková on . Posted in PRF.

Study plan

Study plan

Core courses common to all specializations provide theoretical knowledge and practical skills in the field of modern omics technologies, in the analysis and interpretation of the resulting large data sets and in genome editing.

Core courses - 1st Winter semester

Graduates will further deepen their knowledge and skills in the context of one of the four offered specializations:

Core courses

Core courses are common to all specializations provide theoretical knowledge and practical skills in the field of modern omics technologies, in the analysis and interpretation of the resulting large data sets and in genome editing.
Practical Computing for Biologists KMB/925
The course presents the basic computing tools needed to build automated and reproducible pipelines for biological data analysis, visualization and publication.
Bioinformatics for Biologists KMB/615E
The aim of this course is to introduce students with specialization in biology to the new field of bioinformatics. Students will learn about basic algorithms and tools for analysis of data in biology, how to use databases and bioinformatics software.
Introduction to Omics & Biotechnology KMB/921
The aim of the course is to introduce students to OMICs approaches and biotechnologies in both basic and applied biological and biomedical research and related technologies.
Practicals in Omics & Biotechnology KMB/933
These are 5 block practicals in the last 3 weeks of the semester covering the most commonly used OMICs approaches and gene editing. Three of the multi-day practicals are truly hands-on, two are guided visits to service facilities with the opportunity to try out data analysis.
Seminars in Omics & Biotechnology KMB/926
The individual seminars should serve as highlights for individual specializations and as demonstrations of the potential applications of selected technologies, highlighting the latest hot topics in both basic and applied research.
Essays in Omics & Biotechnology KMB/918
The student will choose a current topic on the application of OMICs technology, biotechnology or genome editing and will elaborate this topic (1) into an essay, which (2) will be presented in a seminar to other students where the topic will be discussed.
The New Statistics for Experimental Biologists KMB/929
The fundamentals of statistical reasoning and applications of data analysis in the realm of biological sciences, including some relatively new methods in statistics (e.g., the use of information criteria and multi-model inference) are the focus of this introductory statistical course.
Bioethics KMB/913
In this course bioethics and its fundamental principles will be introduced. This includes some concepts and methods relevant to all human disciplines, ranging from logic, epistemology, and ontology to general ethics.
Master's English Examination – TOEFL OJZ/930
Testing EAP competencies and communication skills of students on level C1 according to CEFR.
Masters Thesis Assignment KMB/885
The title of the topic of the planned Master Thesis, aims of the research and fundamental sources of information.
Master thesis, Practical part KMB/881
Theoretical preparation for Master´s diploma thesis as well as practical work on the topic of the thesis.
Genetics - Colloquia KMB/180
The objective of this seminar is to provide students with sufficient space for training in giving short lectures concerning either their own results or more general science topics. The experience of students gained in these seminars will be useful in lecturing in symposia and conferences. In parallel, students will have the opportunity to hear lectures given by experienced lecturers.
Cell Structure and Function KMB/914
This course provides students of the program the proper foundation for the basic unit of life, the cell, which decodes the information inherent in DNA.

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Written by Lenka Chodáková on . Posted in PRF.

RNDr. Alena Krejčí, Ph.D. EN

RNDr. Alena Krejčí, Ph.D.

head of the Laboratory of Bee Biology

Faculty of Science, University of South Bohemia
Branišovská 31, 37005 České Budějovice
building B, ground floor, door number 192
 
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Tel. +420 387772270
ORCID ID: 0000-0001-7589-4035 

RNDr. Alena Krejčí, Ph.D.

Current possitions

Group leader since 2019

Laboratory of Bee Biology, Faculty of Science, University of South Bohemia

Previous possitions

Group leader 2010-2019

Laboratory of developmental biology, Faculty of Science, University of South Bohemia
Senior Research Associate 2004-2010

Department of Physiology, Development and Neuroscience, University of Cambridge, United Kingdom, Laboratory of Prof. Sarah Bray
Royal Society fellowship 2001-2004

University of Leeds, School of Biochemistry and Molecular Biology, United Kingdom. Laboratory of Prof. Noel Buckley.
Graduate and Ph. D. studies 1998-2004

Department of Neurochemistry, Institute of Physiology, Academy of Sciences, Prague. Laboratory of Prof. Stanislav Tucek and Dr. Vladimir Dolezal.

Education

PhD in molecular genetics 2004

Faculty of Science, Charles University, Prague

Awards and fellowships

Early Research Career Award 2011

British Biochemical Society 
Award for the best popular science article

Magazine 'Ziva' (in Czech, artical about the Warburg effect)
Winner of the L'Oreal Women in Science award
EMBO long term fellowship 2005-2007

University of Cambridge, UK, laboratory of prof. Sarah Bray
Royal Society fellowship 10 months in total between 2001–2004

School of Biochemistry and Molecular Biology, University of Leeds, UK, Laboratory of Prof. Noel Buckley

Grants

Nutritional supplement for bees with antiviral properties 2019-2022

Grant from the Technology Agency of Czech Republic
Metabolic stress as regulator of Notch signalling. 2017-2019

Grant from the Czech Grant Agency
The role of sirtuins in Notch signalling 2014-2016

Grant from the Czech Grant Agency
Signallization through the Notch receptor in the context of cellular metabolism. 2011-2013

Grant from the Czech Grant Agency
The interplay between Notch signalling and cellular metabolism 2011-2016

EMBO installation grant, Funding of 250k euro total.

Bee keeping experience

  • Active member of the local branch of the Czech beekeeping society and a hobby beekeeper (15 hives)
  • Co-manager of Experimental and educational apiary at the Biology Centre, Ceské Budějovice (30 hives)
  • Popular bee science talks to students and public
  • TV and radio programmes about bees, newspaper interviews
  • Current grant from the Technology Agency of the Czech Republic for antiviral effects of natural ingredience in bee keeping
  • Collaboration with the Department of robotics and embeded systems at the University of south Bohemia - designing a beehive themperature and CO2 sensors, image analysis using neural networks and machine learning

Mentoring

  • Mentor of 2 succesfully defended PhD students (plus 1 writing), 4 master students and 14 bachelor students.

Teaching

  • Molecular biology course (undegrad)
  • Developmental bIology course (undergrad)

Publications

  • Bruce Krejčí A, Krištůfek V: Mravenčí trápení (Tha ant's sorrow). Moderní včelař (Modern Beekeeper) 03, 34-35, 2022.
  • Bruce Krejčí A, Svobodová K, Krištůfek V: Testování kvality vosku stanovením jeho teploty tuhnutí (Testing the wax quality by assesing its setting temperature). Moderní včelař (Modern Beekeeper) 02, 16-18, 2022.
  • Krištůfek V, Bruce Krejčí A, Svobodová K, Chalupský J: Snižují houby virózy a úmrtnost včel? (Do mushrooms lower virus loads and mortality of honey bee colonies?)  Moderní včelař (Modern Beekeeper) 06, 28-30, 2021.
  • Urajová P., Krištůfek V., Bruce Krejčí A: Kyselina para-kumarová a výživa včel (Para-coumaric acid and bee nutrition). Moderní včelař (Modern Beekeeper) 07, 28-30, 2020.
  • Perez-Gomez R, Perez-Gomez R, Magnin V, Mihajlovic Z, Slaninova V and Krejci A: Downregulation of respiratory complex I mediates major signalling changes triggered by TOR activation. Scientific Reports 10, 4401, 2020.
  • Mihajlovic Z, Tanasic D, Bajgar A, Perez-Gomez R, Steffal P, Krejci A: Lime is a new protein linking immunity and metabolism in Drosophila. Developmental Biology 452(2):83-94, 2019.
  • Krejci A, Tennessen JM.: Metabolism in time and space - exploring the frontier of developmental biology. Development 144(18):3193-3198, 2017.
  • Horvath M, Mihajlovic Z, Slaninova V, Perez-Gomez R, Moshkin Y, Krejci A: The silent information regulator 1 (Sirt1) is a positive regulator of the Notch pathway in Drosophila. Biochemical journal 473(22):4129-4143, 2016.
  • Slaninova V, Krafcikova M, Perez-Gomez R, Steffal P, Trantirek L, Bray SJ and Krejci A: Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle. Open Biology, 2016 Feb;6(2)., 2016. doi: 10.1098/rsob.150155.
  • Housden BE, Fu AQ, Krejci A, Bernard F, Fischer B, Tavare S, Russell S, Bray SJ: Transcriptional Dynamics Elicited by a Short Pulse of Notch Activation Involves Feed-Forward Regulation by E(spl)/Hes Genes. Plos Genetics, 9(1):e1003162, 2013.
  • Djiane A, Krejci A, Bernard F, Fexova S, Millen K, Bray SJ.: Dissecting the mechanisms of Notch induced hyperplasia.  EMBO Journal 32, 60 - 71, 2013. doi:
  • Endo K, Karim MR, Taniguchi H, Krejci A, Kinameri E, Siebert M, Ito K., BraySJ, Moore AW: Chromatin modification of Notch targets in olfactory receptor neuron diversification. Nature Neuroscience, 15(2):224-33, 2012. doi: 10.1038/nn.2998.
  • Terriente-Felix A, Li J, Collins S, Mulligan A, Reekie I, Bernard F, Krejci A,  Bray SJ: Notch co-operates with Lozenge/Runx to lock hemocytes into a differentiation programme. Development, 140(4):926-37, 2013. doi: 10.1242/dev.086785
  • Bernard F, Krejci A, Housden B, Adryan B, Bray SJ: Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors. Development, 137(16):2633-42, 2010. doi: 10.1242/dev.053181
  • Krejci A*, Bernard F*, Housden BE*, Collins S, Bray SJ.: Direct response to Notch activation: signaling crosstalk and incoherent logic. Science Signal.,2(55), 2009. doi:10.1126/scisignal.2000140
  • Narasimha M, Uv A, Krejci A, Brown NH, Bray SJ.: Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis. J Cell Sci. 2008. doi: 10.1242/jcs.019422
  • Goodfellow H*, Krejcí A*, Moshkin Y*, Verrijzer CP, Karch F, Bray SJ.: Gene-specific targeting of the histone chaperone asf1 to mediate silencing. Dev Cell.13(4):593-600, 2007.PMID: 17925233
  • Krejci A and Bray S: Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers.  Genes Dev. 21(11):1322-7, 2007. PMID: 17545467
  • Bruce AW, Krejci A, Ooi L, Deuchars J, Wood IC, Dolezal V, Buckley NJ. :The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype. J Neurochem. 98(6):1828-40, 2006. PMID: 16945103
  • Nagel AC, Krejci A, Tenin G, Bravo-Patino A, Bray S, Maier D, Preiss A. : Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol Cell  Biol. 25(23):10433-41, 2005. PMID: 16287856
  • Jakubik J, Krejci A, Dolezal V: Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators. J Pharmacol Exp Ther. 313(2):688-96, 2005.
  • Krejci A, Bruce AW, Tucek S, Dolezal V, Buckley NJ: Multiple promoters drive tissue specific expression of the human M2 muscarinic acetylcholine receptor gene. J Neurochem. 91(1):88-98, 2004.
  • Tucek S, Krejci A, Lysikova M, Jakubik J, Dolezal V: Roles of external loops of muscarinic receptors in interactions between N-methylscopolamine and allosteric modulators. In Cholinergic mechanisms: Function and disfunction. Ed. I. Silman, 71-76, 2004.
  • Krejci A, Michal P, Jakubik J, Ricny J, Dolezal V: Regulation of signal transduction at M2 muscarinic receptor. Physiol. Res., 53, suppl.1:S131-40, 2004.
  • Krejci A, Tucek S: Quantitation of mRNAs for M1 to M5 subtypes of muscarinic receptors in rat heart and brain cortex. Mol Pharmacol.  61(6):1267-72, 2002.
  • Krejci A, Tucek S: Changes of cooperativity between N-methylscopolamine and allosteric modulator alcuronium and gallamine induced by mutations of external loops of muscarinic M3 receptors. Mol. Pharmacol. 60 : 761-767, 2001.

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