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Written by Vilém Tláskal on 14 February 2024. Posted in PRF.

Molecular and Cell Biology and Genetics

Department of Molecular Biology and Genetics

Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

The aim of the program is to (1) deepen students' knowledge of molecular and cell biology and genetics and (2) prepare students for independent professional / scientific work in the laboratory. Students therefore take lectures and practical courses necessary for application not only in modern biological research, either basic or applied, but also in practice in forensic and clinical laboratories and biotechnology companies. The aim is to educate independent graduates who are familiar with the most modern approaches of molecular biology and genetics and are able to process and present the results of scientific work. The result of the study is also an experimentally oriented diploma thesis, which should have the ambition to become a basis for a scientific publication.

The acquired knowledge and skills will enable the graduate to continue his / her academic career in doctoral studies primarily in the fields of cell and molecular biology and genetics, but also in the fields of molecular physiology, biochemistry, biomedicine and, in certain cases, bioinformatics. Thanks to the modern wide application of molecular biology, however, graduates have a very good chance to find their place in the application sphere - in clinical diagnostic laboratories, forensic genetic laboratories, or as service specialists and technicians in various service laboratories and biotechnology companies.

Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics, located at the Faculty of Science and closely cooperating institutes of the Biology Center ASCR. These areas include the characterization of molecular and cellular processes such as cyanobacteria photosynthesis, metabolism and gene expression in parasitic protozoa to find new targets for treatment, ticks immune processes and pathogen transfer mechanisms, cellular signaling on the classical model organism Drosophila melanogaster, epigenetic mechanisms in plant models. Further studies of molecular evolution and characterization of unicellular eukaryotes, molecular mechanisms of co-evolution of host and parasite / symbiont, molecular cytogenetics and study of sex chromosome evolution in arthropods, through cytogenetics and genomic approaches in plant models. Scientific interests also include studying molecular mechanisms that affect biological processes at the whole organism level, such as regulating metabolism during immune response in the Drosophila melanogaster model, studying insect hormonal regulation and diapause, and studying the molecular mechanisms of circadian and photoperiodic clocks in insects. Last but not least, it is also the study of the regulation of early mouse development and molecular mechanisms of insect development.

A prospective student should complete in his previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

KMB 218 Epigenetics
KMB 759 Genetics - the Molecular Approach
KMB 358 Introduction to Genomics
KMB 217 Methods of Functional Genomics
KMB 602E Advanced methods in molecular biology 2
KEBR 631 Bioenergetics
KMB 613 Bioinformatics for Biologists
KMB 223 Techniques of microscopy and image analysis for biologists

If needed to complete previous education:

KMB 219 Introduction to Cell Biology (also basic genetics)
KMB 758 Molecular Biology and Genetics I
KBO 759 Biostatistics
UCH 757 Biochemistry 1.
UCH 643 Biochemistry 2.
KMB 770 Methods in molecular biology

All courses available for the program in English:

Winter semester
UCH/769 Environmental Chemistry 2
UCH/768 Environmental Chemistry Laboratory 3
UCH/758 Biochemistry Laboratory 1 3
UCH/757 Biochemistry 1 4
UCH/061 Applications of Molecular Modelling 2
UCH/060 Computational Chemistry and Molecular Modelling of Biomolecules 4
UCH/058 Developmental and Comparative Biochemistry 3
UCH/045 Glycobiochemistry 3
UCH/037 Basic techniques in practical chemistry1 3
UCH/027 X-ray Crystallography 4
UCH/024 Biochemistry at the Service of Medicine 3
UCH/021 Enzymology 3
UCH/020 Genetic and Protein Engineering 4
UCH/010 Seminar in Advanced Biological Chemistry 1
UCH/ZBE Principles of Experimental Methods in Biology 4
UCH/BCH Introduction to biochemistry 4
KBE/760 Biology of Microorganisms 5
KBE/115 Strategic Planning in Forest and Nature Conservation 4
KBE/546 Ecosystem Management Course 3
KBO/759 Biostatistics 5
KBO/184 Creative Publishing in Community Ecology 4
KBO/297 Functional Traits in Ecology 5
KEBR/631 Bioenergetics 4
KEBR/220 Plant Physiology 8
KMB/758 Molecular Biology and Genetics I 3
KMB/759 Molecular Biology and Genetics II 3
KMB/770 Methods in Molecular Biology 4
KME/772 Clinical Biochemistry 3
KPA/604 Molecular Phylogenetics 4
KZO/412I Molecular Ecology 6
KZO/141 Tropical insects 3
OJZ/650 Technical Writing 3
UAI/735I Python Basics 4
UAI/665 Data Mining in Bioinformatics 4
UAI/652 Programming of iPad/iPhone 4
UAI/650 Algorithms and Data Structures 4
UAI/756 CISCO Academy I 3
UAI/670 Ethics 3
UFY/PPI Parallel Programming 4
UFY/ZVK Technical English IV – Basics of Scientific Communication: Writing and Speaking 3
UFY/EM1 Electron Microscopy I 4
UMB/564I Calculus I 6
UMB/551I Linear Algebra 3

Summer semester
UCH/011 Seminar in Advanced Biological Chemistry II 1
UCH/773 WHO/EU Laboraroty and Regulatory Procedures 3
UCH/647 Biopharmacy 3
UCH/645 Principles of anticancer and antiviral drug development I. 3
UCH/040 Biomolecular NMR Spectroscopy 3
UCH/033 Fluorescence Spectroscopy in Biological Systems 3
UCH/030 General Chemistry 3
UCH/643 Biochemistry 2 4
UCH/022 Protein Chemistry 4
UCH/642 Biochemistry Laboratory 2 5
UCH/052 Xenobiochemistry and Toxicology 5
UCH/BIT Biotechnology 5
UCH/960 Drug Design 3
UCH/BII Bioinformatics 4
UCH/254 Crystallization Course 8
KBE/019 Social Ecology of Local Rural Systems 4
KBE/322 Plant Physiological Ecology (note:offered every other year) 6
KBE/128 Introduction to Functional Ecology (note:offered every other year) 6
KBE/352 Seminars in Wetland Ecology 3
KBE/427 Wetland Ecology (note:offered every other year) 6
KBO/767 Biology of Plants 3
KEBR/619 Stable isotopes in biology and ecology2 6
KMB/605 Introduction to Bioinformatics 5
KMB/358 Introduction to Genomics 3
KME/733 Immunology for Biological Chemistry - laboratory 2
KME/723 Immunology 2
KME/615 Cell Line Cultures in Vitro 3
KME/083 Virology for Biological Chemistry - laboratory 2
KME/082 Virology 3
KZO/768 Biology of Animals 3
KZO/068 Diversity of Life 5
KZO/055 Evolution of the Brain and Intelligence 3
UAI/729I Project Management and its Economy 6
UAI/683I Advanced Database Systems 3
UAI/655 Applied Programming 3
UAI/609 Computer Hardware 6
UAI/757 CISCO Academy II 3
UFY/EM2 Electron Microscopy II 4
UFY/KTS Quantum Theory and Spectroscopy 6
UMB/565I Calculus II 5

Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

If needed to complete previous education:

All courses available for the program in English:

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Written by Blanka Bodnárová on 06 February 2024. Posted in PRF.

Býčí skála Cave

Seznam štítků: PŘF

LAPE is involved in the investigations of the Býčí Skála Cave site, one of the most important Central European sites of the Hallstatt period, led by the Department of History at the Faculty of Arts, Palacký University in Olomouc (Martin Golec) and the Department of Archaeology at the Faculty of Arts, Charles University (Zuzana Golec Mírová). The current research aims to revise previous findings from 1872 concerning the Hallstatt discovery in the Entrance Hall of Býčí Skála Cave, well known particularly thanks to the significant number of human remains and luxury items.

The current revision research project and excavation from the 2020–2021 project employ various natural scientific methods to reveal local environmental issues and bring new insights into past human funerary behaviour and associated material evidence. LAPE is particularly involved in analysing charcoals and plant macroremains, discovering exceptionally preserved deposits of food remains. The archaeobotanical material from the Býčí Skála Cave consists of a rich “burial” layer, which, for example, contains numerous finds of millet, barley, wheat, poppy, and pulses. Among the archaeobotanical material, there are also findings of some aquatic organisms testifying to the aquatic environment (e.g. daphnia). that was associated with burial rituals.

byci-skala

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Written by Blanka Bodnárová on 06 February 2024. Posted in PRF.

The Neolithic in South Bohemia

The project focuses on the Neolithic settlement of a specific region of South Bohemia, which was settled during the secondary wave of the spread of the Linear Pottery culture and was only sporadically settled in the later phases of the Neolithic. The project studies settlement dynamics, transregional contacts, and subsistence strategies of local farmers and their interaction with the natural environment of the region. It can be assumed that in the peripheral zones of Neolithic settlement, there may have been adaptations and diversification of the cultural habitat that we know from the better-studied core areas of Neolithic settlement.

The project's principal investigator is Václav Vondrovský from the Institute of Archaeology of the CAS in Prague and the Institute of Archaeology of the Faculty of Arts of the University of South Bohemia in České Budějovice. The Laboratory of Archaeobotany and Palaeoecology of the Faculty of Science of the University of South Bohemia in České Budějovice provides environmental analyses and participates in solving questions related to the natural environment and subsistence strategies of the first farmers in the region.

Team members:

Václav Vondrovský
Michaela Ptáková
Martin Pták
Jiří Bumerl
Petr Šída

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Written by Blanka Bodnárová on 06 February 2024. Posted in PRF.

Medieval landscape

The long-term goal of the Laboratory of Archaeobotany and Palaeoecology is closely related to archaeobotanical research at several Czech archaeological sites. It was significantly strengthened in 2018-2022 when the department worked with the Czech University of Life Sciences in Prague on the Protection of Historical Plužinas project. The research on medieval landscapes essentially builds on this effort by processing the rich dataset that is now available. Examples of medieval sites studied include Debrné near Trutnov, the landscape around Oblík in the Central Bohemian Uplands or the agricultural hinterland of historic settlements around Rokštejn Castle in the Jihlava region.

The research project focuses on the question of dating medieval landscape transformation, on the types of medieval settlements and their agricultural background in selected parts of Bohemia, Moravia and Silesia, on the question of vegetation changes during the period of medieval colonisation and on the innovative use of archaeobotany and chemistry in archaeological research.

Team members:

Jaromír Beneš
Jiří Bumerl
Veronika Komárková
Tereza Majerovičová
Ivana Šitnerová
Kristýna Budilová

stredoveka-krajina-autor-tomas-junek

Photo author: Tomáš Jůnek

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Written by Marek Kincl on 19 January 2024. Posted in PRF.

Decision of the dean on the rules of admission for the Master's Functional Genetics and Bioinformatics programme for the academic year 2024/2025

Decision

of the dean on the rules of admission for the Master's

Functional Genetics and Bioinformatics programme for

the academic year 2024/2025

In accordance with Sections 48 - 50 of Act 111/1998 Coll. on Higher Education Institutions and the Modifications and Amendments of Other Acts, I announce the rules of admission for entrance into the master study programme Ecology at the Faculty of Science, University of South Bohemia in České Budějovice (hereafter FSci USB) for the academic year 2024/2025.

Article 1. Study programme opened

Programme	Number of applicants admitted
Functional Genetics and Bioinformatics	35

Article 2. Admission deadlines

a) Main term

Applications may be submitted until 19 May 2024 together with required documents specified in Art. 3. Applicants must submit a certified copy of proof of successful completion of the Bachelor's degree[1] no later than 13 June 2024, 11:00 a.m.

b) Additional term

Students are admitted to fill vacant capacities in the programme. Applications may be submitted from 1 July to 31 October 2024 together with required documents specified in Art. 3. Applicants must submit a certified copy of proof of successful completion of the Bachelor's degree¹ no later than 6 February 2025, 11:00 a.m.

For documents issued by a foreign university, the faculty reserves the right to request higher forms of verification or nostrification.

Article 3. Application submission

Applications must be submitted online at https://wstag.jcu.cz/portal/studium/uchazec/eprihlaska.html?pc_lang=en The application fee of CZK 700 can be paid by credit card through the JCU payment gateway or by bank transfer to account number 104725778/0300; variable symbol - 6020106, specific symbol - electronic application number generated by the electronic application system. Applicants are advised to agree with electronic communication (to be expressed in the application).

As attachments the application must be submitted following documents:

a) Applicant´s CV;
b) The motivational letter introducing the applicant, his/her interests and previous experience in the field, and describing their bachelor' s research project(s), if any, on up to one A4 page;
c) A proof of English language proficiency. Certificates at level B2 and higher according to the Ministry of Education, Youth and Sports's list of standardized examinations are accepted. An official TOEFL score of 180 (computer-based test) or higher, or a score of 500 (paper-based test) or higher are accepted as well. The applicant does not have to provide it if he/she has passed the final Bachelor's exam in English at the FSci USB with a grade better than or equal to "very good minus" or if he/she comes from a country where English is the main language[2].

The applicant shall deliver the documents of previous education in person or by post to the Department of Student Affairs of the Faculty of Science at the following address:

Department of Student Affairs,
Faculty of Science
University of South Bohemia
Branišovská 1760
370 05 České Budějovice
Czech Republic

Article 4. Eligible applicants

Admitted to study may be an applicant holding a Bachelor’s degree who fulfils the conditions set out in Art. 5. of this Decision.

Article 5. Entrance exam

a) The dean is to name an admission committee composed of 3-6 members of the academic staff. In the first round, the applications and motivational letters are evaluated by the admission committee on the following aspects:

research interests, experience, and plans,
ability to communicate in English at a level sufficient for the st

b) Each member of the committee is to evaluate each applicant's application and motivational letter on a scale of 0-10 points, the points are then to be averaged across all committee members. Applicants are to be ranked by score and 60 applicants with the highest score are then to be invited for the second round (interview). All applicants reaching the same score as the 60^th applicant are also to be invited. Applicants scoring below 3 points are not to be admitted.

c) Applicants invited to the second round are to be interviewed via teleconferencing (e.g. Zoom). The candidates to be interviewed are to be notified within one week after the application deadline and the date and time of their interview arranged with them.

During the interview the admission committee is to examine the:

scope of knowledge in molecular and cell biology, genetics and bioinformatics,
research interests, experience, and plans,
ability to communicate in English at a level sufficient for the study.

d) Each member of the committee is to evaluate each applicant's performance on a scale of 0-10 points, and the points are to be averaged across all committee members. Applicants are ranked by the score and 20 applicants with the highest score are admitted. All applicants reaching the same score as the 20^th applicant are also to be admitted. Applicants scoring below 3 points are not to be

e) Based on the recommendation of the admission committee, the dean is to decide and announce the admission or non-admission of the given applicant within three weeks of the examination in case the applicant delivered the Bachelor diploma before applicant´s interview, otherwise within one week after diploma submission deadline. This information is to be passed on to the applicant by e-mail and post.

Article 6. Applicants with special needs

An applicant with special needs (with a disability, chronic illness, or other health problems) has the right to use the support measures and services provided by the university during the entrance examination and, if accepted, also during their study. If they wish to assert this claim, they must select the option YES in the column “Consideration of special needs” in the online application form. After fulfilling all the administrative requirements associated with the application for study they will be contacted by the staff of the Support Centre for Students with Special Needs and acquainted with the next steps. More detailed information can be obtained on the centre's website (www.centrumssp.jcu.cz), by email (This email address is being protected from spambots. You need JavaScript enabled to view it.) or by telephone (00420 389 036 026). It is also possible to consult with the staff of the centre about the suitability of choice of a study programme before submitting an application for study.

Article 7. Further provisions

a) Applicants who, no later than the fifth working day after the scheduled date of the entrance examination, submit a physician's certificate attesting to their unfitness to participate in the examination or will experience technical problems during the interview, will be invited to the examination on an alternative date, organized in the same way as the examination on the original date.

b) Unsuccessful applicants shall have the right to appeal to the Dean within 30 days of receiving the decision. If the appeal is rejected, the candidate may present it to the Rector of the University for a final decision. The appeal is to target Art. 5 of this Decision, otherwise it is to be deemed to be without basis. In formulating the appeal the applicant has the right to view the documentation of his admission process but does not have the right to see the documentation of other applicants or the committee

These conditions for admission were discussed and agreed upon by the Academic Senate of Faculty of Science, University of South Bohemia in České Budějovice on 16 January 2024.

České Budějovice, 19 January 2024

prof. RNDr. František Vácha, Ph.D.
The Dean of the Faculty of Science

[1] Applicants holding a Bachelor degree from the USB do not have to submit the proof of education.

[2] Australia, anglophone Canada, Ireland, New Zealand, United Kingdom, United States of America, South Africa

PDF download here

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