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Written by Lenka Chodáková on . Posted in PRF.

Master studies

Department of Molecular Biology and Genetics

Master studies

  • Functional genetics and bioinformatics

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  • Molecular and Cell Biology and Genetics

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Master studies

Functional genetics and bioinformatics 

Master program

Guarantor: prof. Alexander W. Bruce, Ph.D.

Applications open: February 2024
Application deadline: 19 May 2024

Study start: September 2024
Study duration: 2 years

e-application

  • The new 2-year Master's study program Functional genetics and bioinformatics was created with support of the National Recovery Plan for Higher Education for 2022-2024 (NPO Trasformace-JU, reg. č. NPO_JČU_MŠMT-16608/2022) to increase the career prospects of our graduates by implementing rapidly developing new technologies changing both the field and the global labor market.
    The program offers four different specializations:
    Functional genetics and bioinformatics: Bioinformatics
    Functional genetics and bioinformatics:     Biotechnology 
    Functional genetics and bioinformatics: Human molecular genetics 
    Functional genetics and bioinformatics: Molecular cell biology and genetics

  • The new technologies increasingly require graduates to be adept at performing and analyzing experiments generating large data sets and to be able to translate their findings into meaningful biological results supported by a high level of theoretical knowledge. The main goals of the new study program are to expand the knowledge of students in the field of modern biological research on a theoretical and practical level and thus prepare them for future occupations in applied research and development in the industrial, agricultural, clinical or service sectors (e.g. in pharmaceutical or biotechnological industry or clinical diagnostics) and to positions in academic research (e.g. by continuing to doctoral studies).

  • Graduates of the program will acquire modern skills and knowledge in the field of so-called omics methods (i.e. high-capacity analysis of the genome, transcriptome, proteome or metabolome) and genetic engineering, which represent a technological revolution in biological research and increasingly contribute to breakthrough discoveries in biology and medicine. Graduates of the program will also be able to use or even develop bioinformatics tools for the analysis of large biological data produced by the omics approaches. Studies in the new program will be conducted entirely in English, which will increase the international competitiveness of its graduates and the attractiveness of studies for foreign students. Students will thus be educated in an international and multidisciplinary environment that will better reflect the reality of work in an increasingly globalized and integrated world economy.

  • Emphasis is placed on the support of independent scientific work and independent critical thinking within the framework of experimentally oriented diploma thesis, which can stand a rigorous professional evaluation and can be the basis for scientific publications. Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics (Faculty of Science) and closely cooperating institutes of the Biology Center of the Czech Academy of Sciences (CAS) and the Centre of Algal Biotechnology of the Institute of Microbiology CAS. These areas include characterization of molecular and cellular processes (photosynthesis, metabolism, immunity, and cell signaling) and studies of development, genome organisation and molecular evolution in both classical models and non-model organisms.

  • A prospective student should have background in biology, biomedicine or biochemistry and complete in their previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

  •  

  • Tuition fees

    There are no tuition fees*, only application fee 700 CZK (approx. 30 EUR)

    * Studies in foreign language are normally subject to tuition fees of 3000 EUR, however these do not apply to the Functional genetics and bioinformatics due to its funding through National Recovery Plan for Higher Education.

  •  

  • How to apply

    You can apply on-line in e-application, but read about the admission procedure first!
    For additional information please contact Department of Student Affairs.

!MORE INFORMATION ABOUT ADMISSION PROCESS SOON!

Study plan


Core courses common to all specializations provide theoretical knowledge and practical skills in the field of modern omics technologies, in the analysis and interpretation of the resulting large data sets and in genome editing.

KMB/925   Practical Computing for Biologists
KMB/615E  Bioinformatics for Biologists
KMB/921   Introduction to Omics & Biotechnology
KMB/933   Practicals in Omics & Biotechnology
KMB/926   Seminars in Omics & Biotechnology
KMB/929   The New Statistics for Experimental Biologists
KMB/913   Bioethics
OJZ/930   Master's English Examination – TOEFL
KMB/885   Masters Thesis Assignment
KMB/881   Master thesis, Practical part
KMB/180   Genetics - Colloquia
KMB/914   Cell Structure and Function
KMB/918   Essays in Omics & Biotechnology

Graduates will further deepen their knowledge and skills in the context of one of the four offered specializations:

  • Functional genetics and bioinformatics: Bioinformatics

    The Bioinformatics specialization combines an understanding of biological questions with advanced bioinformatics and computational skills to analyze large sets of genomic, transcriptomic, and metabolomic data.

     
    Obligatory courses
    KMB/934   BASH Programming
    KMB/922   Introduction to R
    KMB/919   Genomics
    KMB/930   Transcriptomics and Epigenomics
    Obligatory elective courses
    UAI/735I   Python I
    UAI/697E   Databases
    UAI/330E   Data Analysis in Natural Sciences
    UAI/331   Python in Data Sciences
    KMB/924   Molecular Physiology and Metabolism
    KMB/927   Structural Bioinformatics
    KPA/604   Molecular Phylogenetics
    KZO/412I   Molecular Ecology
    KPA/172   Microbial Ecology and Genomics
  • Study plan - specialization Bioinformatics

  • Functional genetics and bioinformatics: Biotechnology

    The Biotechnology specialization provides advanced theoretical knowledge and skills in the field of genetic engineering, microbial biotechnology (for example, algal biotechnology for the manipulation of photosynthesis or the production of new bioactive substances) and plant and animal biotechnology (for example aquaculture biotechnology or new approaches using sequencing and editing of genomes in the breeding of economic crops).

     
    Obligatory courses:
    UCH/020   Gene & Protein Engineering
    KMB/928   Molecular Biology & Biotechnology of Cyanobacteria
    KBE/262E   Microbial Biotechnology
    KMB/937   Plant Biotechnology
    VURH/xxx   Animal Biotechnology
    Obligatory elective courses:
    KMB/924   Molecular Physiology and Metabolism
    KMB/920   Industrial Enzymology
    KEBR/631   Bioenergetics
    KMB/912   Algal Biotechnology
    KMB/936   Biotechnological & Molecular Techniques in Crop Management
  • Study plan - specialization Biotechnology

  • Functional genetics and bioinformatics: Human molecular genetics

    The Human molecular genetics specialization provides knowledge and skills in the areas of clinical genetics and genomics, state-of-the-art molecular diagnostic methods (based on next-generation sequencing), mechanisms of human diseases and methodological approaches to their research and treatment, including personalized medicine and gene therapy.

    Obligatory courses:
    KMB/932   Fundamental Human Genetics
    KMB/923   Molecular Mechanisms of Disease
    KMB/915   Clinical Genetics & Genomics
    KMB/917   Diagnosis of Human Disease
    KME/744E   Trends in Biomedicine
    Obligatory elective courses:
    KMB/618   Epigenetics & Regulation of Gene Expression
    KME/087E   Molecular Immunology
    KMB/924   Molecular Physiology and Metabolism
    KMB/927   Structural Bioinformatics
    KMB/602E   Advanced Methods of Molecular Biology 2
    KMB/916   Developmental Biology – Molecular Perspective
    KMB/935   Cytogenomics
  • Study plan - specialization Human molecular genetics

  • Functional genetics and bioinformatics: Molecular cell biology and genetics

    The specialization Molecular cell biology and genetics provides broad knowledge and practical skills that can be used especially in basic but also translational research, understanding of life processes and physiology at the level of molecules, cells and cell sub-compartments, tissues and model (mouse, fruit fly, caterpillar) and non-model organisms, always with an emphasis on the application of modern omic approaches and editing of genetic information.

    Obligatory courses:
    KMB/916   Developmental Biology – Molecular Perspective
    KMB/931   Model Organisms in Biomedical Research
    KMB/618E   Epigenetics & Regulation of Gene Expression
    KMB/602E   Advanced Methods of Molecular Biology 2
    KMB/924   Molecular Physiology and Metabolism
    Obligatory elective courses:
    UCH/012E   Thermodynamics of Biomolecular Systems
    UCH/014E   Structural Biochemistry
    KMB/221E   Evolutionary Genetics
    KEBR/631    Bioenergetics
    KMB/935    Cytogenomics
    KMB/910     Introduction to Virology
     
  • Study plan - specialization Molecular cell biology and genetic

Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

The aim of the program is to (1) deepen students' knowledge of molecular and cell biology and genetics and (2) prepare students for independent professional / scientific work in the laboratory. Students therefore take lectures and practical courses necessary for application not only in modern biological research, either basic or applied, but also in practice in forensic and clinical laboratories and biotechnology companies. The aim is to educate independent graduates who are familiar with the most modern approaches of molecular biology and genetics and are able to process and present the results of scientific work. The result of the study is also an experimentally oriented diploma thesis, which should have the ambition to become a basis for a scientific publication.

The acquired knowledge and skills will enable the graduate to continue his / her academic career in doctoral studies primarily in the fields of cell and molecular biology and genetics, but also in the fields of molecular physiology, biochemistry, biomedicine and, in certain cases, bioinformatics. Thanks to the modern wide application of molecular biology, however, graduates have a very good chance to find their place in the application sphere - in clinical diagnostic laboratories, forensic genetic laboratories, or as service specialists and technicians in various service laboratories and biotechnology companies.

Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics, located at the Faculty of Science and closely cooperating institutes of the Biology Center ASCR. These areas include the characterization of molecular and cellular processes such as cyanobacteria photosynthesis, metabolism and gene expression in parasitic protozoa to find new targets for treatment, ticks immune processes and pathogen transfer mechanisms, cellular signaling on the classical model organism Drosophila melanogaster, epigenetic mechanisms in plant models. Further studies of molecular evolution and characterization of unicellular eukaryotes, molecular mechanisms of co-evolution of host and parasite / symbiont, molecular cytogenetics and study of sex chromosome evolution in arthropods, through cytogenetics and genomic approaches in plant models. Scientific interests also include studying molecular mechanisms that affect biological processes at the whole organism level, such as regulating metabolism during immune response in the Drosophila melanogaster model, studying insect hormonal regulation and diapause, and studying the molecular mechanisms of circadian and photoperiodic clocks in insects. Last but not least, it is also the study of the regulation of early mouse development and molecular mechanisms of insect development.

A prospective student should complete in his previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

KMB 218 Epigenetics
KMB 759 Genetics - the Molecular Approach
KMB 358 Introduction to Genomics
KMB 217 Methods of Functional Genomics
KMB 602E Advanced methods in molecular biology 2
KEBR 631 Bioenergetics
KMB 613 Bioinformatics for Biologists
KMB 223 Techniques of microscopy and image analysis for biologists

If needed to complete previous education:

KMB 219 Introduction to Cell Biology (also basic genetics)
KMB 758 Molecular Biology and Genetics I
KBO 759 Biostatistics
UCH 757 Biochemistry 1.
UCH 643 Biochemistry 2.
KMB 770 Methods in molecular biology

All courses available for the program in English:

Winter semester
UCH/769 Environmental Chemistry 2
UCH/768 Environmental Chemistry Laboratory 3
UCH/758 Biochemistry Laboratory 1 3
UCH/757 Biochemistry 1 4
UCH/061 Applications of Molecular Modelling 2
UCH/060 Computational Chemistry and Molecular Modelling of Biomolecules 4
UCH/058 Developmental and Comparative Biochemistry 3
UCH/045 Glycobiochemistry 3
UCH/037 Basic techniques in practical chemistry1 3
UCH/027 X-ray Crystallography 4
UCH/024 Biochemistry at the Service of Medicine 3
UCH/021 Enzymology 3
UCH/020 Genetic and Protein Engineering 4
UCH/010 Seminar in Advanced Biological Chemistry 1
UCH/ZBE Principles of Experimental Methods in Biology 4
UCH/BCH Introduction to biochemistry 4
KBE/760 Biology of Microorganisms 5
KBE/115 Strategic Planning in Forest and Nature Conservation 4
KBE/546 Ecosystem Management Course 3
KBO/759 Biostatistics 5
KBO/184 Creative Publishing in Community Ecology 4
KBO/297 Functional Traits in Ecology 5
KEBR/631 Bioenergetics 4
KEBR/220 Plant Physiology 8
KMB/758 Molecular Biology and Genetics I 3
KMB/759 Molecular Biology and Genetics II 3
KMB/770 Methods in Molecular Biology 4
KME/772 Clinical Biochemistry 3
KPA/604 Molecular Phylogenetics 4
KZO/412I Molecular Ecology 6
KZO/141 Tropical insects 3
OJZ/650 Technical Writing 3
UAI/735I Python Basics 4
UAI/665 Data Mining in Bioinformatics 4
UAI/652 Programming of iPad/iPhone 4
UAI/650 Algorithms and Data Structures 4
UAI/756 CISCO Academy I 3
UAI/670 Ethics 3
UFY/PPI Parallel Programming 4
UFY/ZVK Technical English IV – Basics of Scientific Communication: Writing and Speaking 3
UFY/EM1 Electron Microscopy I 4
UMB/564I Calculus I 6
UMB/551I Linear Algebra 3

Summer semester
UCH/011 Seminar in Advanced Biological Chemistry II 1
UCH/773 WHO/EU Laboraroty and Regulatory Procedures 3
UCH/647 Biopharmacy 3
UCH/645 Principles of anticancer and antiviral drug development I. 3 
UCH/040 Biomolecular NMR Spectroscopy 3
UCH/033 Fluorescence Spectroscopy in Biological Systems 3
UCH/030 General Chemistry 3
UCH/643 Biochemistry 2 4
UCH/022 Protein Chemistry 4
UCH/642 Biochemistry Laboratory 2 5
UCH/052 Xenobiochemistry and Toxicology 5
UCH/BIT Biotechnology 5
UCH/960 Drug Design 3
UCH/BII Bioinformatics 4
UCH/254 Crystallization Course 8
KBE/019 Social Ecology of Local Rural Systems 4
KBE/322 Plant Physiological Ecology (note:offered every other year) 6
KBE/128 Introduction to Functional Ecology (note:offered every other year) 6
KBE/352 Seminars in Wetland Ecology 3
KBE/427 Wetland Ecology (note:offered every other year) 6
KBO/767 Biology of Plants 3
KEBR/619 Stable isotopes in biology and ecology2 6
KMB/605 Introduction to Bioinformatics 5
KMB/358 Introduction to Genomics 3
KME/733 Immunology for Biological Chemistry - laboratory 2
KME/723 Immunology 2
KME/615 Cell Line Cultures in Vitro 3
KME/083 Virology for Biological Chemistry - laboratory 2
KME/082 Virology 3
KZO/768 Biology of Animals 3
KZO/068 Diversity of Life 5
KZO/055 Evolution of the Brain and Intelligence 3
UAI/729I Project Management and its Economy 6
UAI/683I Advanced Database Systems 3
UAI/655 Applied Programming 3
UAI/609 Computer Hardware 6
UAI/757 CISCO Academy II 3
UFY/EM2 Electron Microscopy II 4
UFY/KTS Quantum Theory and Spectroscopy 6
UMB/565I Calculus II 5

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Written by Vilém Tláskal on . Posted in PRF.

Functional genetics and bioinformatics

Functional genetics and bioinformatics 

Master program

Department of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic


Applications open: February 2024
Application deadline: 19 May 2024
Online interview:  1-2 weeks after application deadline


Course details:
Start date: September 2024
Duration: 2 years
In person on-site

  • The new 2-year Master's study program Functional genetics and bioinformatics was created with support of the National Recovery Plan for Higher Education for 2022-2024 (NPO Trasformace-JU, reg. č. NPO_JČU_MŠMT-16608/2022) to increase the career prospects of our graduates by implementing rapidly developing new technologies changing both the field and the global labor market.
    The program offers four different specializations:
    Functional genetics and bioinformatics: Bioinformatics
    Functional genetics and bioinformatics:     Biotechnology 
    Functional genetics and bioinformatics: Human molecular genetics 
    Functional genetics and bioinformatics: Molecular cell biology and genetics

  • The new technologies increasingly require graduates to be adept at performing and analyzing experiments generating large data sets and to be able to translate their findings into meaningful biological results supported by a high level of theoretical knowledge. The main goals of the new study program are to expand the knowledge of students in the field of modern biological research on a theoretical and practical level and thus prepare them for future occupations in applied research and development in the industrial, agricultural, clinical or service sectors (e.g. in pharmaceutical or biotechnological industry or clinical diagnostics) and to positions in academic research (e.g. by continuing to doctoral studies).

  • Graduates of the program will acquire modern skills and knowledge in the field of so-called omics methods (i.e. high-capacity analysis of the genome, transcriptome, proteome or metabolome) and genetic engineering, which represent a technological revolution in biological research and increasingly contribute to breakthrough discoveries in biology and medicine. Graduates of the program will also be able to use or even develop bioinformatics tools for the analysis of large biological data produced by the omics approaches. Studies in the new program will be conducted entirely in English, which will increase the international competitiveness of its graduates and the attractiveness of studies for foreign students. Students will thus be educated in an international and multidisciplinary environment that will better reflect the reality of work in an increasingly globalized and integrated world economy.

  • Emphasis is placed on the support of independent scientific work and independent critical thinking within the framework of experimentally oriented diploma thesis, which can stand a rigorous professional evaluation and can be the basis for scientific publications. Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics (Faculty of Science) and closely cooperating institutes of the Biology Center of the Czech Academy of Sciences (CAS) and the Centre of Algal Biotechnology of the Institute of Microbiology CAS. These areas include characterization of molecular and cellular processes (photosynthesis, metabolism, immunity, and cell signaling) and studies of development, genome organisation and molecular evolution in both classical models and non-model organisms.

  • A prospective student should have background in biology, biomedicine or biochemistry and complete in their previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Study plan


Core courses common to all specializations provide theoretical knowledge and practical skills in the field of modern omics technologies, in the analysis and interpretation of the resulting large data sets and in genome editing.

KMB/925   Practical Computing for Biologists
KMB/615E  Bioinformatics for Biologists
KMB/921   Introduction to Omics & Biotechnology
KMB/933   Practicals in Omics & Biotechnology
KMB/926   Seminars in Omics & Biotechnology
KMB/929   The New Statistics for Experimental Biologists
KMB/913   Bioethics
OJZ/930   Master's English Examination – TOEFL
KMB/885   Masters Thesis Assignment
KMB/881   Master thesis, Practical part
KMB/180   Genetics - Colloquia
KMB/914   Cell Structure and Function
KMB/918   Essays in Omics & Biotechnology

 

Graduates will further deepen their knowledge and skills in the context of one of the four offered specializations:

  • Functional genetics and bioinformatics: Bioinformatics

    The Bioinformatics specialization combines an understanding of biological questions with advanced bioinformatics and computational skills to analyze large sets of genomic, transcriptomic, and metabolomic data.

     
    Obligatory courses
    KMB/934   BASH Programming
    KMB/922   Introduction to R
    KMB/919   Genomics
    KMB/930   Transcriptomics and Epigenomics
    Obligatory elective courses
    UAI/735I   Python I
    UAI/697E   Databases
    UAI/330E   Data Analysis in Natural Sciences
    UAI/331   Python in Data Sciences
    KMB/924   Molecular Physiology and Metabolism
    KMB/927   Structural Bioinformatics
    KPA/604   Molecular Phylogenetics
    KZO/412I   Molecular Ecology
    KPA/172   Microbial Ecology and Genomics
  • Study plan - specialization Bioinformatics

  • Functional genetics and bioinformatics: Biotechnology

    The Biotechnology specialization provides advanced theoretical knowledge and skills in the field of genetic engineering, microbial biotechnology (for example, algal biotechnology for the manipulation of photosynthesis or the production of new bioactive substances) and plant and animal biotechnology (for example aquaculture biotechnology or new approaches using sequencing and editing of genomes in the breeding of economic crops).

     
    Obligatory courses:
    UCH/020   Gene & Protein Engineering
    KMB/928   Molecular Biology & Biotechnology of Cyanobacteria
    KBE/262E   Microbial Biotechnology
    KMB/937   Plant Biotechnology
    VURH/xxx   Animal Biotechnology
    Obligatory elective courses:
    KMB/924   Molecular Physiology and Metabolism
    KMB/920   Industrial Enzymology
    KEBR/631   Bioenergetics
    KMB/912   Algal Biotechnology
    KMB/936   Biotechnological & Molecular Techniques in Crop Management
  • Study plan - specialization Biotechnology

  • Functional genetics and bioinformatics: Human molecular genetics

    The Human molecular genetics specialization provides knowledge and skills in the areas of clinical genetics and genomics, state-of-the-art molecular diagnostic methods (based on next-generation sequencing), mechanisms of human diseases and methodological approaches to their research and treatment, including personalized medicine and gene therapy.

    Obligatory courses:
    KMB/932   Fundamental Human Genetics
    KMB/923   Molecular Mechanisms of Disease
    KMB/915   Clinical Genetics & Genomics
    KMB/917   Diagnosis of Human Disease
    KME/744E   Trends in Biomedicine
    Obligatory elective courses:
    KMB/618   Epigenetics & Regulation of Gene Expression
    KME/087E   Molecular Immunology
    KMB/924   Molecular Physiology and Metabolism
    KMB/927   Structural Bioinformatics
    KMB/602E   Advanced Methods of Molecular Biology 2
    KMB/916   Developmental Biology – Molecular Perspective
    KMB/935   Cytogenomics
  • Study plan - specialization Human molecular genetics

  • Functional genetics and bioinformatics: Molecular cell biology and genetics

    The specialization Molecular cell biology and genetics provides broad knowledge and practical skills that can be used especially in basic but also translational research, understanding of life processes and physiology at the level of molecules, cells and cell sub-compartments, tissues and model (mouse, fruit fly, caterpillar) and non-model organisms, always with an emphasis on the application of modern omic approaches and editing of genetic information.

    Obligatory courses:
    KMB/916   Developmental Biology – Molecular Perspective
    KMB/931   Model Organisms in Biomedical Research
    KMB/618E   Epigenetics & Regulation of Gene Expression
    KMB/602E   Advanced Methods of Molecular Biology 2
    KMB/924   Molecular Physiology and Metabolism
    Obligatory elective courses:
    UCH/012E   Thermodynamics of Biomolecular Systems
    UCH/014E   Structural Biochemistry
    KMB/221E   Evolutionary Genetics
    KEBR/631    Bioenergetics
    KMB/935    Cytogenomics
    KMB/910     Introduction to Virology
     
  • Study plan - specialization Molecular cell biology and genetic

  • How to apply

    You can apply on-line in e-application, but read about the admission procedure first!

    The application procedure follows the Decision of the dean on the rules of admission for the Master's Functional Genetics and Bioinformatics programme for the academic year 2024/2025.

    You can apply by submitting:

    E-application: an on-line form with your personal data

    CV and motivation letter: introduce yourself; explain your motivation and interest in the study programme, and your previous research experience

    A proof of English language proficiency*: certificates at CEFR B2 level and higher or an official computer-based TOEFL test score of 180 or higher, or a paper-based TOEFL test score of 500 or higher. The proof is not needed if you passed the final Bachelor's exam in English at the Faculty of Science of the University of South Bohemia with a grade better than or equal to "very good minus" or if you come from a country where English is the main language, that is Australia, anglophone Canada, Ireland, New Zealand, United Kingdom, United States of America, South Africa.

    In the first round of the admission procedure, the admission committee evaluates research interests, experience, and plans based on motivation letters. The shortlisted applicants are invited for video conferencing interview. Besides their research interests and experience, the applicants can be also asked for their background in molecular and cell biology, genetics, and bioinformatics.

    A certified copy of the Bachelor’s degree needs to be submitted by 13 June 2024*. Then decision on the admission or non-admission will be made within one week after diploma submission deadline at latest.

    * Applicants may request documents to be submitted at a later date by emailing the Department of Student Affairs.

    Please also check the General Information for prospective students, for additional information please contact Department of Student Affairs.

     

    Important dates:

    Applications open: February 2024

    Application deadline: 19 May 2024

    On-line interview:  1-2 weeks after application deadline

    Study start: September 2024

    Study duration: 2 years

     

  • Tuition fees

     

    There are no tuition fees**, only application fee 700 CZK *** (approx. 30 EUR)

    ** Studies in foreign language are normally subject to tuition fees of 3000 EUR, however these do not apply to the Functional Genetics and Bioinformatics due to its funding through National Recovery Plan for Higher Education.

    *** The application fee of CZK 700 can be paid by credit card through the JCU payment gateway or by bank transfer to account number 104725778/0300; variable symbol - 6020106, specific symbol - electronic application number generated by the electronic application system. 

     

    Certification of Bachelor's degree

    You need to submit a certified hardcopy of your Bachelor's diploma that will be recognized by our Vice-dean for Bachelor and Master Studies. The types of diplomas/certificates and legal requirements differ widely between countries. It is therefore recommended to send the Department of Student Affairs (This email address is being protected from spambots. You need JavaScript enabled to view it.) a scan of your documents for pre-checking. The Department will inform you about any further requirements. There are various levels of document authentication and translation to Czech or English may be required in some cases.

    International administration - visa

    Depending on your nationality and status, you might have to apply for a visa or residence permit to enter and study in the Czech Republic. You should start your visa application as soon as possible as the whole procedure can take several months. Information about visas are available on our website at https://www.jcu.cz/study-at-usb/practical-info/immigration-visa-information

    Contact the Department of Student Affairs (This email address is being protected from spambots. You need JavaScript enabled to view it.) for assistence.

Research project supervision

The programme supports independent scientific work through an experimentally oriented diploma thesis. The research project is worth 33 ECTS credits (out of 120 total) and its focus falls mainly in areas of interest of researchers associated under the Department of Molecular Biology and Genetics. However, research projects under supervision of external mentors are also possible. For more options, check research done at closely cooperating institutes of the Biology Center of the Czech Academy of Sciences (CAS) and the Centre of Algal Biotechnology of the Institute of Microbiology CAS.

Senior researchers affiliated with the Department

prof. Alexander W. Bruce, Ph.D.
is interested in molecular mechanisms that underpin mammalian preimplantation embryo development; specifically the derivation of the first three cell lineages (trophectoderm, primitive endoderm & epiblast) that arise by the time of embryo uterine implantation.

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prof. RNDr. Josef Komenda, CSc., DSc. 
uses a model cyanobacterium Synechocystis to study mechanisms and regulation of the assembly of membrane pigment-protein complexes and their quality control. He particularly focuses on the role of structural subunits and auxiliary protein factors in the process of Photosystem II assembly.

prof. RNDr. Julius Lukeš, CSc.
is interested in functional analysis of mitochondrial proteins of the kinetoplastid Trypanosoma brucei to establish their functions in RNA editing and regulation of stability of mitochondrial transcripts and respiration. He is also interested in the evolution and biodiversity of parasitic kinetoplastid flagellates.

prof. Ing. Miroslav Oborník, Ph.D.
is interested in photosynthetic organelles of unicellular photoautotrophic eukaryotes and complex plastids of apicomplexan parasites that evolved through secondary endosymbiogenesis. He is mainly involved in the search for nuclear-encoded plastid targeted proteins, their in silico localization and phylogeny.

prof. RNDr. Ivo Šauman, Ph.D.
his research revolves around the ways in which organisms synchronize their biorhythms with environmental oscillations. The long-term goal of his research is to learn more about the cellular and molecular mechanisms regulating circadian rhythms.

doc. Mgr. Tomáš Doležal, Ph.D.
is interested in metabolic regulation of energy distribution into different organs during Drosophila melanogaster  immune response. He analyzes tissue-specific gene expression, signaling and metabolites throughout the infection and tests the impacts of various genetic manipulations on systemic physiology.

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prof. Ing. Roman Sobotka, Ph.D.
studies various aspects of oxygenic photosynthesis in cyanobacteria. A long term interest is the mechanistic insight on the biogenesis and photoprotection of photosynthetic apparatus and the chlorophyll biosynthesis pathway. A favorite organism is the model cyanobacterium Synechocystis PCC 6803. The laboratory utilizes a broad spectrum of methods, from genetics and biochemistry, various Omics techniques, in silico calculations to structural methods.

doc. Mgr. Hassan Hashimi, Ph.D.
investigates the evolution of mitochondria, the oldest extant endosymbiont in eukaryotes. He is particularly interested in cristae, the morphological character of mitochondria that literally give the organelle the room to breathe. He works with protists with weird cristae and mitochondria: Trypanosoma brucei and ciliates.

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RNDr. Drahomíra Faktorová, Ph.D.
is interested mainly in diplonemids, unicellular marine flagellates that were recently found to be one of the most abundant and diverse marine protists. Using diplonemids as a model we investigate functions of the most abundant eukaryotic proteins through a variety of molecular biology techniques and assays.   

RNDr. Alena Krejčí, Ph.D.
focuses on both basic and applied research of honey bee resistance to diseases. She investigates how bee thermoregulation, nutrition and apiary management practice influence the development of viral infections and other diseases.

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RNDr. Petr Nguyen, Ph.D.
combines cytogenetic and genomic approaches to study the role of genome organization and its changes in evolution. He is interested in evolutionary drivers of sex chromosome turnover and a role of neo-sex chromosomes in speciation.

Mgr. Adam Bajgar, Ph.D.
investigates functional versatility of Drosophila macrophages in the context of diverse physiological processes such as regulation of metabolism during infections, metamorphosis and development. His team has recently established several tools for manipulation of macrophages in non-model insect species.

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RNDr. Radmila Čapková Frydrychová, Ph.D.
is interested in cell senescence caused by shortening of nucleoprotein structures at chromosome ends, the telomeres. She investigates the role of telomerase, an enzyme that adds short repetitive DNA sequences to the chromosome ends, in the regulation of aging in social insects.

Mgr. Hana Sehadová, Ph.D.
is interested in insect neuroanatomy, histology, and microscopy. She studies how living organisms perceive oscillations in external environmental stimuli such as light and temperature that precisely synchronize their internal biological clocks on a daily basis.

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Mgr. David Doležel, Ph.D.
uses various model and non-model insects to explore important questions of chronobiology and insect physiology. He combines reverse genetics approaches (RNAi, genome editing), omic approaches (genomics, transcriptomics, peptidomics), in vitro techniques (tissue cultures, yeast two-hybrid assay), microsurgical interventions and behavioral experiments.

 

 

 

Mgr. Michaela Fencková, Ph.D.
focuses on genetic and molecular control of neural development and cognition in health and disease. Using Drosophila as a model, she studies genes that are important for cognitive function and investigates how a single genetic defect can result in dramatic and severe neurodevelopmental disorders, such as intellectual disability or autism.

Mgr. Martin Kolísko, Ph.D.
employs comparative genomics and transcriptomics to understand the evolution of parasitism. Specifically, he seeks to understand the evolutionary mechanisms of the transition from a free-living organism to a parasitic mode of life and, conversely, from a parasitic mode of life back to a free-living mode of life.

RNDr. Petr Kopáček, CSc.
focuses on molecular descriptions of proteins that are key for the successful blood-feeding of ticks (mainly Ixodes ricinus) and the red poultry mite (Dermanyssus gallinae), or play a role in the acquisition & transmission of tick-borne pathogens.

Ing. Petr Novák, Ph.D.
is interested in repetitive DNA sequences and their impact on genome organization and evolution and development of novel bioinformatics approaches for de novo identification and characterization of repetitive elements from genomic shotgun sequencing data obtained by next-generation technologies.

doc. RNDr. Alena Panicucci Zíková, Ph.D.
is interested in medically important parasitic African trypanosomes. She focuses particularly on signals and molecular mechanisms driving metabolic remodeling and ultrastructural changes of mitochondria associated with complex parasitic life cycles involving mammalian hosts and insect vectors. 

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prof. RNDr. Michal Žurovec, CSc.
focuses on insect cell growth regulators. He particularly studies adenosine signalling and regulation of energetic homeostasis in insect cells. Besides that, he is interested in targeted mutagenesis and characterisation of silk proteins.

 Mgr. Iva Mozgová, Ph.D.
is interested in epigenetic mechanisms underlying plant responses to environmental conditions. Her research focuses on the histone-modifying Polycomb repressive complexes (PRCs), the evolutionarily conserved protein complexes, that control seed-to-seedling transition in flowering plants

RNDr. Zdeněk Paris, Ph.D.
investigates various aspects of RNA biology of the protozoan parasite Trypanosoma brucei and related flagellates with a long term goal of identifying unique mechanisms of their RNA metabolism. He is mainly interested in processes such as tRNA modifications, nuclear tRNA export and role of the only intron containing tRNA in trypanosomes.

Mgr. Lenka Gahurová, Ph.D.
uses various sequencing and imaging approaches to study evolutionary history and molecular (especially epigenetic) mechanisms of long-term female fertility at the levels of oocytes, ovarian niche, and successful embryonic development in short-lived and long-lived non-model rodents.

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Mgr. Aleš Horák, Ph.D.
deals with various aspects of evolutionary biology of protists and characterization of diversity, ecological role and metabolic potential of those unicellular eukaryotes; that represent majority of Earth’s biodiversity but cannot be kept in permanent cultures, using the power of the next-generation sequencing and bioinformatics.

prof. RNDr. Marek Jindra, CSc.
is interested in the receptor of juvenile hormone (JH), which regulates multiple aspects of insect development, reproduction, and physiology. His goal is to harness the juvenile hormone receptor to study the molecular action of JH in insect biology and identify novel compounds for safe and selective pest control.

Ing. Martin Moos, Ph.D.
and his team are developing novel bioanalytical approaches and apply them into metabolite research of insects and other important living organims. Unique analytical platforms developed by the team cover the analysis of a comprehensive set of metabolites, from small molecules derived from organic and amino acids, amines, over nucleosides, nucleotides, lipids, steroids, sugars or their conjugates to peptide sequencing.

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Mgr. Anzhelika Butenko, Ph.D.
studies evolution of gene repertoire in Euglenozoa, a group of unicellular eukaryotes that includes Trypanosoma and Leishmania pathogens. She investigates genetic changes that underlie lifestyle switches and the genes that define ecological success of these organisms. using omics data and cutting-edge bioinformatics methods.

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MSc. Galina Prokopchuk, Ph.D.
is interested in exploring the behavior of microorganisms, with a particular focus on marine diplonemids. Her research focuses on understanding different aspects such as ecology, ultrastructure, movement, predator-prey dynamics and molecular biology of various marine protists. She also investigates the roles of different protist proteins, particularly those whose functions remain unknown.

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RNDr. Martin Volf, Ph.D.
is interested in the evolution of plant-herbivore interactions, particularly from the perspective of plant chemical defences. One of his main topics is exploring how different environmental pressures contribute towards the astonishing diversity of specialized metabolites among plant species.

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RNDr. Pável Matos-Maraví, Ph.D.
is interested in phylogenomics and population genomics of tropical insects (mainly butterflies). His aim is to understand the evolutionary drivers of speciation and biogeographical assemblages. His research team uses ecological and species traits datasets, which are coupled with whole-genome resequencing data and bioinformatics.

Research projects

  • Alexander W. Bruce

    Laboratory of Early Mammalian Developmental Biology (LEMDB)

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  • Tomáš Doležal

    Laboratory of Integrative Biology in Drosophila

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  • Alena Krejčí

    Laboratory of Bee Biology

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  • Lenka Gahurová

    Mammalian Developmental Epigenetics and Bioinformatics

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  • Adam Bajgar

    Insect Immunometabolism

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  • Anzhelika Butenko

    Molecular Biology of Protist

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  • Galina Prokopchuk

    Molecular Biology of Protists

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  • Hana Sehadová

    Chronobiology, Neuroanatomy, Histology and microscopy

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  • Martin Volf

    Evolutionary Ecology

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  • Alena Panicucci Zíková

    Functional Biology of Protists

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  • Martin Moos

    Analytical Biochemistry and Metabolomics

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Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

The aim of the program is to (1) deepen students' knowledge of molecular and cell biology and genetics and (2) prepare students for independent professional / scientific work in the laboratory. Students therefore take lectures and practical courses necessary for application not only in modern biological research, either basic or applied, but also in practice in forensic and clinical laboratories and biotechnology companies. The aim is to educate independent graduates who are familiar with the most modern approaches of molecular biology and genetics and are able to process and present the results of scientific work. The result of the study is also an experimentally oriented diploma thesis, which should have the ambition to become a basis for a scientific publication.

The acquired knowledge and skills will enable the graduate to continue his / her academic career in doctoral studies primarily in the fields of cell and molecular biology and genetics, but also in the fields of molecular physiology, biochemistry, biomedicine and, in certain cases, bioinformatics. Thanks to the modern wide application of molecular biology, however, graduates have a very good chance to find their place in the application sphere - in clinical diagnostic laboratories, forensic genetic laboratories, or as service specialists and technicians in various service laboratories and biotechnology companies.

Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics, located at the Faculty of Science and closely cooperating institutes of the Biology Center ASCR. These areas include the characterization of molecular and cellular processes such as cyanobacteria photosynthesis, metabolism and gene expression in parasitic protozoa to find new targets for treatment, ticks immune processes and pathogen transfer mechanisms, cellular signaling on the classical model organism Drosophila melanogaster, epigenetic mechanisms in plant models. Further studies of molecular evolution and characterization of unicellular eukaryotes, molecular mechanisms of co-evolution of host and parasite / symbiont, molecular cytogenetics and study of sex chromosome evolution in arthropods, through cytogenetics and genomic approaches in plant models. Scientific interests also include studying molecular mechanisms that affect biological processes at the whole organism level, such as regulating metabolism during immune response in the Drosophila melanogaster model, studying insect hormonal regulation and diapause, and studying the molecular mechanisms of circadian and photoperiodic clocks in insects. Last but not least, it is also the study of the regulation of early mouse development and molecular mechanisms of insect development.

A prospective student should complete in his previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

KMB 218 Epigenetics
KMB 759 Genetics - the Molecular Approach
KMB 358 Introduction to Genomics
KMB 217 Methods of Functional Genomics
KMB 602E Advanced methods in molecular biology 2
KEBR 631 Bioenergetics
KMB 613 Bioinformatics for Biologists
KMB 223 Techniques of microscopy and image analysis for biologists

If needed to complete previous education:

KMB 219 Introduction to Cell Biology (also basic genetics)
KMB 758 Molecular Biology and Genetics I
KBO 759 Biostatistics
UCH 757 Biochemistry 1.
UCH 643 Biochemistry 2.
KMB 770 Methods in molecular biology

All courses available for the program in English:

Winter semester
UCH/769 Environmental Chemistry 2
UCH/768 Environmental Chemistry Laboratory 3
UCH/758 Biochemistry Laboratory 1 3
UCH/757 Biochemistry 1 4
UCH/061 Applications of Molecular Modelling 2
UCH/060 Computational Chemistry and Molecular Modelling of Biomolecules 4
UCH/058 Developmental and Comparative Biochemistry 3
UCH/045 Glycobiochemistry 3
UCH/037 Basic techniques in practical chemistry1 3
UCH/027 X-ray Crystallography 4
UCH/024 Biochemistry at the Service of Medicine 3
UCH/021 Enzymology 3
UCH/020 Genetic and Protein Engineering 4
UCH/010 Seminar in Advanced Biological Chemistry 1
UCH/ZBE Principles of Experimental Methods in Biology 4
UCH/BCH Introduction to biochemistry 4
KBE/760 Biology of Microorganisms 5
KBE/115 Strategic Planning in Forest and Nature Conservation 4
KBE/546 Ecosystem Management Course 3
KBO/759 Biostatistics 5
KBO/184 Creative Publishing in Community Ecology 4
KBO/297 Functional Traits in Ecology 5
KEBR/631 Bioenergetics 4
KEBR/220 Plant Physiology 8
KMB/758 Molecular Biology and Genetics I 3
KMB/759 Molecular Biology and Genetics II 3
KMB/770 Methods in Molecular Biology 4
KME/772 Clinical Biochemistry 3
KPA/604 Molecular Phylogenetics 4
KZO/412I Molecular Ecology 6
KZO/141 Tropical insects 3
OJZ/650 Technical Writing 3
UAI/735I Python Basics 4
UAI/665 Data Mining in Bioinformatics 4
UAI/652 Programming of iPad/iPhone 4
UAI/650 Algorithms and Data Structures 4
UAI/756 CISCO Academy I 3
UAI/670 Ethics 3
UFY/PPI Parallel Programming 4
UFY/ZVK Technical English IV – Basics of Scientific Communication: Writing and Speaking 3
UFY/EM1 Electron Microscopy I 4
UMB/564I Calculus I 6
UMB/551I Linear Algebra 3

Summer semester
UCH/011 Seminar in Advanced Biological Chemistry II 1
UCH/773 WHO/EU Laboraroty and Regulatory Procedures 3
UCH/647 Biopharmacy 3
UCH/645 Principles of anticancer and antiviral drug development I. 3 
UCH/040 Biomolecular NMR Spectroscopy 3
UCH/033 Fluorescence Spectroscopy in Biological Systems 3
UCH/030 General Chemistry 3
UCH/643 Biochemistry 2 4
UCH/022 Protein Chemistry 4
UCH/642 Biochemistry Laboratory 2 5
UCH/052 Xenobiochemistry and Toxicology 5
UCH/BIT Biotechnology 5
UCH/960 Drug Design 3
UCH/BII Bioinformatics 4
UCH/254 Crystallization Course 8
KBE/019 Social Ecology of Local Rural Systems 4
KBE/322 Plant Physiological Ecology (note:offered every other year) 6
KBE/128 Introduction to Functional Ecology (note:offered every other year) 6
KBE/352 Seminars in Wetland Ecology 3
KBE/427 Wetland Ecology (note:offered every other year) 6
KBO/767 Biology of Plants 3
KEBR/619 Stable isotopes in biology and ecology2 6
KMB/605 Introduction to Bioinformatics 5
KMB/358 Introduction to Genomics 3
KME/733 Immunology for Biological Chemistry - laboratory 2
KME/723 Immunology 2
KME/615 Cell Line Cultures in Vitro 3
KME/083 Virology for Biological Chemistry - laboratory 2
KME/082 Virology 3
KZO/768 Biology of Animals 3
KZO/068 Diversity of Life 5
KZO/055 Evolution of the Brain and Intelligence 3
UAI/729I Project Management and its Economy 6
UAI/683I Advanced Database Systems 3
UAI/655 Applied Programming 3
UAI/609 Computer Hardware 6
UAI/757 CISCO Academy II 3
UFY/EM2 Electron Microscopy II 4
UFY/KTS Quantum Theory and Spectroscopy 6
UMB/565I Calculus II 5

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Written by Vilém Tláskal on . Posted in PRF.

Molecular and Cell Biology and Genetics

Department of Molecular Biology and Genetics

Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

The aim of the program is to (1) deepen students' knowledge of molecular and cell biology and genetics and (2) prepare students for independent professional / scientific work in the laboratory. Students therefore take lectures and practical courses necessary for application not only in modern biological research, either basic or applied, but also in practice in forensic and clinical laboratories and biotechnology companies. The aim is to educate independent graduates who are familiar with the most modern approaches of molecular biology and genetics and are able to process and present the results of scientific work. The result of the study is also an experimentally oriented diploma thesis, which should have the ambition to become a basis for a scientific publication.

The acquired knowledge and skills will enable the graduate to continue his / her academic career in doctoral studies primarily in the fields of cell and molecular biology and genetics, but also in the fields of molecular physiology, biochemistry, biomedicine and, in certain cases, bioinformatics. Thanks to the modern wide application of molecular biology, however, graduates have a very good chance to find their place in the application sphere - in clinical diagnostic laboratories, forensic genetic laboratories, or as service specialists and technicians in various service laboratories and biotechnology companies.

Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics, located at the Faculty of Science and closely cooperating institutes of the Biology Center ASCR. These areas include the characterization of molecular and cellular processes such as cyanobacteria photosynthesis, metabolism and gene expression in parasitic protozoa to find new targets for treatment, ticks immune processes and pathogen transfer mechanisms, cellular signaling on the classical model organism Drosophila melanogaster, epigenetic mechanisms in plant models. Further studies of molecular evolution and characterization of unicellular eukaryotes, molecular mechanisms of co-evolution of host and parasite / symbiont, molecular cytogenetics and study of sex chromosome evolution in arthropods, through cytogenetics and genomic approaches in plant models. Scientific interests also include studying molecular mechanisms that affect biological processes at the whole organism level, such as regulating metabolism during immune response in the Drosophila melanogaster model, studying insect hormonal regulation and diapause, and studying the molecular mechanisms of circadian and photoperiodic clocks in insects. Last but not least, it is also the study of the regulation of early mouse development and molecular mechanisms of insect development.

A prospective student should complete in his previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

KMB 218 Epigenetics
KMB 759 Genetics - the Molecular Approach
KMB 358 Introduction to Genomics
KMB 217 Methods of Functional Genomics
KMB 602E Advanced methods in molecular biology 2
KEBR 631 Bioenergetics
KMB 613 Bioinformatics for Biologists
KMB 223 Techniques of microscopy and image analysis for biologists

If needed to complete previous education:

KMB 219 Introduction to Cell Biology (also basic genetics)
KMB 758 Molecular Biology and Genetics I
KBO 759 Biostatistics
UCH 757 Biochemistry 1.
UCH 643 Biochemistry 2.
KMB 770 Methods in molecular biology

All courses available for the program in English:

Winter semester
UCH/769 Environmental Chemistry 2
UCH/768 Environmental Chemistry Laboratory 3
UCH/758 Biochemistry Laboratory 1 3
UCH/757 Biochemistry 1 4
UCH/061 Applications of Molecular Modelling 2
UCH/060 Computational Chemistry and Molecular Modelling of Biomolecules 4
UCH/058 Developmental and Comparative Biochemistry 3
UCH/045 Glycobiochemistry 3
UCH/037 Basic techniques in practical chemistry1 3
UCH/027 X-ray Crystallography 4
UCH/024 Biochemistry at the Service of Medicine 3
UCH/021 Enzymology 3
UCH/020 Genetic and Protein Engineering 4
UCH/010 Seminar in Advanced Biological Chemistry 1
UCH/ZBE Principles of Experimental Methods in Biology 4
UCH/BCH Introduction to biochemistry 4
KBE/760 Biology of Microorganisms 5
KBE/115 Strategic Planning in Forest and Nature Conservation 4
KBE/546 Ecosystem Management Course 3
KBO/759 Biostatistics 5
KBO/184 Creative Publishing in Community Ecology 4
KBO/297 Functional Traits in Ecology 5
KEBR/631 Bioenergetics 4
KEBR/220 Plant Physiology 8
KMB/758 Molecular Biology and Genetics I 3
KMB/759 Molecular Biology and Genetics II 3
KMB/770 Methods in Molecular Biology 4
KME/772 Clinical Biochemistry 3
KPA/604 Molecular Phylogenetics 4
KZO/412I Molecular Ecology 6
KZO/141 Tropical insects 3
OJZ/650 Technical Writing 3
UAI/735I Python Basics 4
UAI/665 Data Mining in Bioinformatics 4
UAI/652 Programming of iPad/iPhone 4
UAI/650 Algorithms and Data Structures 4
UAI/756 CISCO Academy I 3
UAI/670 Ethics 3
UFY/PPI Parallel Programming 4
UFY/ZVK Technical English IV – Basics of Scientific Communication: Writing and Speaking 3
UFY/EM1 Electron Microscopy I 4
UMB/564I Calculus I 6
UMB/551I Linear Algebra 3

Summer semester
UCH/011 Seminar in Advanced Biological Chemistry II 1
UCH/773 WHO/EU Laboraroty and Regulatory Procedures 3
UCH/647 Biopharmacy 3
UCH/645 Principles of anticancer and antiviral drug development I. 3 
UCH/040 Biomolecular NMR Spectroscopy 3
UCH/033 Fluorescence Spectroscopy in Biological Systems 3
UCH/030 General Chemistry 3
UCH/643 Biochemistry 2 4
UCH/022 Protein Chemistry 4
UCH/642 Biochemistry Laboratory 2 5
UCH/052 Xenobiochemistry and Toxicology 5
UCH/BIT Biotechnology 5
UCH/960 Drug Design 3
UCH/BII Bioinformatics 4
UCH/254 Crystallization Course 8
KBE/019 Social Ecology of Local Rural Systems 4
KBE/322 Plant Physiological Ecology (note:offered every other year) 6
KBE/128 Introduction to Functional Ecology (note:offered every other year) 6
KBE/352 Seminars in Wetland Ecology 3
KBE/427 Wetland Ecology (note:offered every other year) 6
KBO/767 Biology of Plants 3
KEBR/619 Stable isotopes in biology and ecology2 6
KMB/605 Introduction to Bioinformatics 5
KMB/358 Introduction to Genomics 3
KME/733 Immunology for Biological Chemistry - laboratory 2
KME/723 Immunology 2
KME/615 Cell Line Cultures in Vitro 3
KME/083 Virology for Biological Chemistry - laboratory 2
KME/082 Virology 3
KZO/768 Biology of Animals 3
KZO/068 Diversity of Life 5
KZO/055 Evolution of the Brain and Intelligence 3
UAI/729I Project Management and its Economy 6
UAI/683I Advanced Database Systems 3
UAI/655 Applied Programming 3
UAI/609 Computer Hardware 6
UAI/757 CISCO Academy II 3
UFY/EM2 Electron Microscopy II 4
UFY/KTS Quantum Theory and Spectroscopy 6
UMB/565I Calculus II 5

Molecular and Cell Biology and Genetics

Master program

Guarantor: doc. Mgr. Tomáš Doležal, Ph.D.

Master program Molecular and Cell Biology and Genetics (in Czech language)

General information for prospective students, for additional information please contact Department of Student Affairs.

The aim of the program is to (1) deepen students' knowledge of molecular and cell biology and genetics and (2) prepare students for independent professional / scientific work in the laboratory. Students therefore take lectures and practical courses necessary for application not only in modern biological research, either basic or applied, but also in practice in forensic and clinical laboratories and biotechnology companies. The aim is to educate independent graduates who are familiar with the most modern approaches of molecular biology and genetics and are able to process and present the results of scientific work. The result of the study is also an experimentally oriented diploma thesis, which should have the ambition to become a basis for a scientific publication.

The acquired knowledge and skills will enable the graduate to continue his / her academic career in doctoral studies primarily in the fields of cell and molecular biology and genetics, but also in the fields of molecular physiology, biochemistry, biomedicine and, in certain cases, bioinformatics. Thanks to the modern wide application of molecular biology, however, graduates have a very good chance to find their place in the application sphere - in clinical diagnostic laboratories, forensic genetic laboratories, or as service specialists and technicians in various service laboratories and biotechnology companies.

Experimental diploma theses focus mainly on the areas of interest of scientific groups associated under the Department of Molecular Biology and Genetics, located at the Faculty of Science and closely cooperating institutes of the Biology Center ASCR. These areas include the characterization of molecular and cellular processes such as cyanobacteria photosynthesis, metabolism and gene expression in parasitic protozoa to find new targets for treatment, ticks immune processes and pathogen transfer mechanisms, cellular signaling on the classical model organism Drosophila melanogaster, epigenetic mechanisms in plant models. Further studies of molecular evolution and characterization of unicellular eukaryotes, molecular mechanisms of co-evolution of host and parasite / symbiont, molecular cytogenetics and study of sex chromosome evolution in arthropods, through cytogenetics and genomic approaches in plant models. Scientific interests also include studying molecular mechanisms that affect biological processes at the whole organism level, such as regulating metabolism during immune response in the Drosophila melanogaster model, studying insect hormonal regulation and diapause, and studying the molecular mechanisms of circadian and photoperiodic clocks in insects. Last but not least, it is also the study of the regulation of early mouse development and molecular mechanisms of insect development.

A prospective student should complete in his previous undergraduate studies basic courses of biochemistry, genetics, cell and molecular biology and practical training in basic molecular biology methods.

Courses recommended for the Master program Molecular and Cell Biology and Genetics:

KMB 218 Epigenetics
KMB 759 Genetics - the Molecular Approach
KMB 358 Introduction to Genomics
KMB 217 Methods of Functional Genomics
KMB 602E Advanced methods in molecular biology 2
KEBR 631 Bioenergetics
KMB 613 Bioinformatics for Biologists
KMB 223 Techniques of microscopy and image analysis for biologists

If needed to complete previous education:

KMB 219 Introduction to Cell Biology (also basic genetics)
KMB 758 Molecular Biology and Genetics I
KBO 759 Biostatistics
UCH 757 Biochemistry 1.
UCH 643 Biochemistry 2.
KMB 770 Methods in molecular biology

All courses available for the program in English:

Winter semester
UCH/769 Environmental Chemistry 2
UCH/768 Environmental Chemistry Laboratory 3
UCH/758 Biochemistry Laboratory 1 3
UCH/757 Biochemistry 1 4
UCH/061 Applications of Molecular Modelling 2
UCH/060 Computational Chemistry and Molecular Modelling of Biomolecules 4
UCH/058 Developmental and Comparative Biochemistry 3
UCH/045 Glycobiochemistry 3
UCH/037 Basic techniques in practical chemistry1 3
UCH/027 X-ray Crystallography 4
UCH/024 Biochemistry at the Service of Medicine 3
UCH/021 Enzymology 3
UCH/020 Genetic and Protein Engineering 4
UCH/010 Seminar in Advanced Biological Chemistry 1
UCH/ZBE Principles of Experimental Methods in Biology 4
UCH/BCH Introduction to biochemistry 4
KBE/760 Biology of Microorganisms 5
KBE/115 Strategic Planning in Forest and Nature Conservation 4
KBE/546 Ecosystem Management Course 3
KBO/759 Biostatistics 5
KBO/184 Creative Publishing in Community Ecology 4
KBO/297 Functional Traits in Ecology 5
KEBR/631 Bioenergetics 4
KEBR/220 Plant Physiology 8
KMB/758 Molecular Biology and Genetics I 3
KMB/759 Molecular Biology and Genetics II 3
KMB/770 Methods in Molecular Biology 4
KME/772 Clinical Biochemistry 3
KPA/604 Molecular Phylogenetics 4
KZO/412I Molecular Ecology 6
KZO/141 Tropical insects 3
OJZ/650 Technical Writing 3
UAI/735I Python Basics 4
UAI/665 Data Mining in Bioinformatics 4
UAI/652 Programming of iPad/iPhone 4
UAI/650 Algorithms and Data Structures 4
UAI/756 CISCO Academy I 3
UAI/670 Ethics 3
UFY/PPI Parallel Programming 4
UFY/ZVK Technical English IV – Basics of Scientific Communication: Writing and Speaking 3
UFY/EM1 Electron Microscopy I 4
UMB/564I Calculus I 6
UMB/551I Linear Algebra 3

Summer semester
UCH/011 Seminar in Advanced Biological Chemistry II 1
UCH/773 WHO/EU Laboraroty and Regulatory Procedures 3
UCH/647 Biopharmacy 3
UCH/645 Principles of anticancer and antiviral drug development I. 3 
UCH/040 Biomolecular NMR Spectroscopy 3
UCH/033 Fluorescence Spectroscopy in Biological Systems 3
UCH/030 General Chemistry 3
UCH/643 Biochemistry 2 4
UCH/022 Protein Chemistry 4
UCH/642 Biochemistry Laboratory 2 5
UCH/052 Xenobiochemistry and Toxicology 5
UCH/BIT Biotechnology 5
UCH/960 Drug Design 3
UCH/BII Bioinformatics 4
UCH/254 Crystallization Course 8
KBE/019 Social Ecology of Local Rural Systems 4
KBE/322 Plant Physiological Ecology (note:offered every other year) 6
KBE/128 Introduction to Functional Ecology (note:offered every other year) 6
KBE/352 Seminars in Wetland Ecology 3
KBE/427 Wetland Ecology (note:offered every other year) 6
KBO/767 Biology of Plants 3
KEBR/619 Stable isotopes in biology and ecology2 6
KMB/605 Introduction to Bioinformatics 5
KMB/358 Introduction to Genomics 3
KME/733 Immunology for Biological Chemistry - laboratory 2
KME/723 Immunology 2
KME/615 Cell Line Cultures in Vitro 3
KME/083 Virology for Biological Chemistry - laboratory 2
KME/082 Virology 3
KZO/768 Biology of Animals 3
KZO/068 Diversity of Life 5
KZO/055 Evolution of the Brain and Intelligence 3
UAI/729I Project Management and its Economy 6
UAI/683I Advanced Database Systems 3
UAI/655 Applied Programming 3
UAI/609 Computer Hardware 6
UAI/757 CISCO Academy II 3
UFY/EM2 Electron Microscopy II 4
UFY/KTS Quantum Theory and Spectroscopy 6
UMB/565I Calculus II 5

Read more …Molecular and Cell Biology and Genetics

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Written by Blanka Bodnárová on . Posted in PRF.

Býčí skála Cave

  • Seznam štítků: PŘF

LAPE is involved in the investigations of the Býčí Skála Cave site, one of the most important Central European sites of the Hallstatt period, led by the Department of History at the Faculty of Arts, Palacký University in Olomouc (Martin Golec) and the Department of Archaeology at the Faculty of Arts, Charles University (Zuzana Golec Mírová). The current research aims to revise previous findings from 1872 concerning the Hallstatt discovery in the Entrance Hall of Býčí Skála Cave, well known particularly thanks to the significant number of human remains and luxury items.

The current revision research project and excavation from the 2020–2021 project employ various natural scientific methods to reveal local environmental issues and bring new insights into past human funerary behaviour and associated material evidence. LAPE is particularly involved in analysing charcoals and plant macroremains, discovering exceptionally preserved deposits of food remains. The archaeobotanical material from the Býčí Skála Cave consists of a rich “burial” layer, which, for example, contains numerous finds of millet, barley, wheat, poppy, and pulses. Among the archaeobotanical material, there are also findings of some aquatic organisms testifying to the aquatic environment (e.g. daphnia). that was associated with burial rituals.

byci-skala

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Written by Blanka Bodnárová on . Posted in PRF.

The Neolithic in South Bohemia

The project focuses on the Neolithic settlement of a specific region of South Bohemia, which was settled during the secondary wave of the spread of the Linear Pottery culture and was only sporadically settled in the later phases of the Neolithic. The project studies settlement dynamics, transregional contacts, and subsistence strategies of local farmers and their interaction with the natural environment of the region. It can be assumed that in the peripheral zones of Neolithic settlement, there may have been adaptations and diversification of the cultural habitat that we know from the better-studied core areas of Neolithic settlement.

The project's principal investigator is Václav Vondrovský from the Institute of Archaeology of the CAS in Prague and the Institute of Archaeology of the Faculty of Arts of the University of South Bohemia in České Budějovice. The Laboratory of Archaeobotany and Palaeoecology of the Faculty of Science of the University of South Bohemia in České Budějovice provides environmental analyses and participates in solving questions related to the natural environment and subsistence strategies of the first farmers in the region.

Team members:

  • Václav Vondrovský
  • Michaela Ptáková
  • Martin Pták
  • Jiří Bumerl
  • Petr Šída
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