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PRF

Research

Department of Experimental Plant Biology

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  • Publications

    2024

    Hájek, T., & Urbanová, Z. (2024). Enzyme adaptation in Sphagnum peatlands questions the significance of dissolved organic matter in enzyme inhibition. Science of The Total Environment, 911, 168685. https://doi.org/10.1016/j.scitotenv.2023.168685

    Svobodová, K., Krištůfek, V., Kubásek, J., & Bruce Krejčí, A. (2024). Alcohol extract of the gypsy mushroom (Cortinarius caperatus) inhibits the development of Deformed wing virus infection in western honey bee (Apis mellifera). Journal of Insect Physiology, 152, 104583. https://doi.org/10.1016/J.JINSPHYS.2023.104583

    Weides, S. E., Hájek, T., Liancourt, P., Herberich, M. M., Kramp, R. E., Tomiolo, S., Pacheco‐Riaño, L. C., Tielbörger, K., & Májeková, M. (2024). Belowground niche partitioning is maintained under extreme drought. Ecology, 105(1), e4198. https://doi.org/10.1002/ecy.4198

    2023

    Kubásek, J., Kalistová, T., Janová, J., Askanbayeva, B., Bednář, J., & Šantrůček, J. (2023). 13 CO2 labelling as a tool for elucidating the mechanism of cuticle development: a case of Clusia rosea. The New Phytologist238(1), 202–215. https://doi.org/10.1111/nph.18716

    Kalistová, T., & Janda, M. (2023). Could a cuticle be an active component of plant immunity? Biologia plantarum67, 322-333. https://doi.org/10.32615/bp.2023.037

    Janda, M., Rybak, K., Krassini, L., Meng, C., Feitosa-Junior, O., Stigliano, E., Szulc, B., Sklenar, J., Menke, F. L. H., Malone, J. G., Brachmann, A., Klingl, A., Ludwig, C., & Robatzek, S. (2023). Biophysical and proteomic analyses of Pseudomonas syringae pv. tomato DC3000 extracellular vesicles suggest adaptive functions during plant infection. mBio, 14(4), e0358922. https://doi.org/10.1128/mbio.03589-22

    Awasthi, P., Mishra, A. K., Kocábek, T., Nath, V. S., Mishra, S., Hazzouri, K. M., Sudalaimuthuasari, N., Stajner, N., Jakše, J., Krofta, K., Hájek, T., & Amiri, K. M. A. (2023). CRISPR/Cas9-mediated mutagenesis of the mediator complex subunits MED5a and MED5b genes impaired secondary metabolite accumulation in hop (Humulus lupulus). Plant Physiology and Biochemistry, 201, 107851. https://doi.org/10.1016/j.plaphy.2023.107851

    Visez, N., Hamzé, M., Vandenbossche, K., Occelli, F., de Nadaï, P., Tobon, Y., Hájek, T., & Choël, M. (2023). Uptake of ozone by allergenic pollen grains. Environmental Pollution, 331, 121793. https://doi.org/10.1016/j.envpol.2023.121793

    Krejčová, G., Morgantini, C., Zemanová, H., Lauschke, V. M., Kovářová, J., Kubásek, J., Nedbalová, P., Kamps-Hughes, N., Moos, M., Aouadi, M., Doležal, T., & Bajgar, A. (2023). Macrophage-derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection. The EMBO Journal, e114086. https://doi.org/10.15252/EMBJ.2023114086

    Vondrák, J., Svoboda, S., Zíbarová, L., Štenclová, L., Mareš, J., Pouska, V., Košnar, J., & Kubásek, J. (2023). Alcobiosis, an algal-fungal association on the threshold of lichenisation. Scientific Reports 2023 13:1, 13(1), 1–13. https://doi.org/10.1038/s41598-023-29384-4

    2022

    Kubásek, J., Hájek, T., Duckett, J., Pressel, S., & Šantrůček, J. (2022). Moss stomata do not respond to light and CO2 concentration but facilitate carbon uptake by sporophytes: A gas exchange, stomatal aperture and 13C labelling study. New Phytologist, 230, 1815-1828. https://doi.org/10.1111/nph.17208

    Šantrůček, J. (2022). The why and how of sunken stomata: does the behaviour of encrypted stomata and the leaf cuticle matter? Annals of Botany, 130, 285-300. https://doi.org/10.1093/aob/mcac055

    Janda, M., & Robatzek, S. (2022). Extracellular vesicles from phytobacteria: Properties, functions and uses. Biotechnology advances, 58, 107934. https://doi.org/10.1016/j.biotechadv.2022.107934

    Barrio, I. C., Ehrich, D., Soininen, E. M., Ravolainen, V. T., Bueno, C. G., Gilg, O., Koltz, A. M., Speed, J. D. M., Hik, D. S., Mörsdorf, M., Alatalo, J. M., Angerbjörn, A., Bêty, J., Bollache, L., Boulanger-Lapointe, N., Brown, G. S., Eischeid, I., Giroux, M. A., Hájek, T., et al. (2022). Developing common protocols to measure tundra herbivory across spatial scales. Arctic Science, 8(3), 638-679. https://doi.org/10.1139/as-2020-0020

    Kosová, V., Hájek, T., Hadincová, V., & Münzbergová, Z. (2022). The importance of ecophysiological traits in response of Festuca rubra to changing climate. Physiologia Plantarum, 174(1), e13608. https://doi.org/10.1111/ppl.13608

    Kubásek, J., Svobodová, K., Půta, F., & Krejčí, A. B. (2022). Honeybees control the gas permeability of brood and honey cappings. iScience, 25(11), 105445. https://doi.org/10.1016/J.ISCI.2022.105445

    2021

    Kubásek, J., Hájek, T., Duckett, J., Pressel, S., & Šantrůček, J. (2021). Moss stomata do not respond to light and CO2 concentration but facilitate carbon uptake by sporophytes: a gas exchange, stomatal aperture and 13C labelling study. New Phytologist, 230(5), 1815-1828. https://doi.org/10.1111/nph.17208

    Lubbe, F. C., Bitomský, M., Hájek, T., de Bello, F., Doležal, J., Jandová, V., Janeček, Š., Bartušková, A., Lanta, V., & Klimešová, J. (2021). A tale of two grasslands: how belowground storage organs coordinate their traits with water-use traits. Plant and Soil, 465(1-2), 533-548. https://doi.org/10.1007/s11104-021-05031-7

    Jílková, V., Devetter, M., Bryndová, M., Hájek, T., Kotas, P., Luláková, P., Meador, T., Navrátilová, D., Saccone, P., & Macek, P. (2021). Carbon Sequestration Related to Soil Physical and Chemical Properties in the High Arctic. Global Biogeochemical Cycles, 35(9), e2020GB006877. https://doi.org/10.1029/2020GB006877

    Martínková, J., Hájek, T., Adamec, L., & Klimešová, J. (2021). Growth, root respiration and photosynthesis of a root-sprouting short-lived herb after severe biomass removal. Flora, 284, 151915. https://doi.org/10.1016/j.flora.2021.151915

    Urbanová, Z., & Hájek, T. (2021). Revisiting the concept of ‘enzymic latch’ on carbon in peatlands. Science of The Total Environment, 779, 146384. https://doi.org/10.1016/j.scitotenv.2021.146384

    Angst, G., Pokorný, J., Mueller, C. W., Prater, I., Preusser, S., Kandeler, E., Meador, T., Straková, P., Hájek, T., van Buiten, G., & Angst, Š. (2021). Soil texture affects the coupling of litter decomposition and soil organic matter formation. Soil Biology and Biochemistry, 159, 108302. https://doi.org/10.1016/j.soilbio.2021.108302

    Májeková, M., Hájek, T., Albert, Á. J., de Bello, F., Doležal, J., Götzenberger, L., Janeček, Š., Lepš, J., Liancourt, P., & Mudrák, O. (2021). Weak coordination between leaf drought tolerance and proxy traits in herbaceous plants. Functional Ecology, 35(6), 1299-1311. https://doi.org/10.1111/1365-2435.13792

    Vráblová, M., Marková, D., Vrábl, D., Koutník, I., Sokolová, B., & Hronková, M. (2021). Surface plasmon resonance: An innovative method for studying water permeability of plant cuticles. Plant Science, 310. https://doi.org/10.1016/j.plantsci.2021.110978

    Voon, C. P., Law, Y.-S., Guan, X., Lim, S.-L., Xu, Z., Chu, W.-T., Zhang, R., Sun, F., Labs, M., Leister, D., Pribil, M., Hronková, M., Kubásek, J., Cui, Y., Jiang, L., Tsuyama, M., Gardeström, P., Tikkanen, M., & Lim, B. L. (2021). Modulating the activities of chloroplasts and mitochondria promotes adenosine triphosphate production and plant growth. Quantitative Plant Biology, 2. https://doi.org/10.1017/qpb.2021.7

    2020

    Hájek, T. (2020). Interlinking moss functional traits. A commentary on: ‘Mechanisms behind species-specific water economy responses to water level drawdown in peat mosses’. Annals of Botany, 126(2), iv-v. https://doi.org/10.1093/aob/mcaa108

    Vicherová, E., Glinwood, R., Hájek, T., Šmilauer, P., & Ninkovic, V. (2020). Bryophytes can recognize their neighbours through volatile organic compounds. Scientific Reports, 10(1), 7405. https://doi.org/10.1038/s41598-020-64108-y

    Tveit, A. T., Kiss, A., Winkel, M., Horn, F., Hájek, T., Svenning, M. M., Wagner, D., & Liebner, S. (2020). Environmental patterns of brown moss- and Sphagnum-associated microbial communities. Scientific Reports, 10(1), 22412. https://doi.org/10.1038/s41598-020-79773-2

    Liancourt, P., Song, X., Macek, M., Santrucek, J., & Dolezal, J. (2020). Plant's-eye view of temperature governs elevational distributions. Global Change Biology, 26, 4094-4103. https://doi.org/10.1111/gcb.15129

    Canarini, A., Wanek, W., Watzka, M., Sandén, T., Spiegel, H., Šantrůček, J., & Schnecker, J. (2020). Quantifying microbial growth and carbon use efficiency in dry soil environments via 18O water vapor equilibration. Global Change Biology, 26, 5333-5341.  https://doi.org/10.1111/gcb.15168

    Hůnová, I., Hanusková, D., Jandová, K., Tesař, M., Květoň, J., Kukla, J. (2020). Estimates of the contribution of fog water to wet atmospheric deposition in Czech mountain forests based on its stable hydrogen and oxygen isotope composition: Preliminary results. European journal of environmental sciences, 10(2,) 89-97. https://doi.org/10.14712/23361964.2020.10

    Šolcová, A., Jamrichová, E., Horsák, M., Pařil, P., Petr, L., Heiri, O., Květoň, J., Křížek, M., Hartvich, F., Hájek, M., Hájková, P. (2020). Abrupt vegetation and environmental change since the MIS 2: A unique paleorecord from Slovakia (Central Europe). Quaternary Science Reviews, 230, 106170. https://doi.org/10.1016/j.quascirev.2020.106170

    Vráblová, M., Hronková, M., Vrábl, D., Kubásek, J., & Šantrůček, J. (2018). Light intensity-regulated stomatal development in three generations of Lepidium sativum. Environmental and Experimental Botany, 156. https://doi.org/10.1016/j.envexpbot.2018.09.012

    Vráblová, M., Vrábl, D., Sokolová, B., Marková, D., & Hronková, M. (2020). A modified method for enzymatic isolation of and subsequent wax extraction from Arabidopsis thaliana leaf cuticle. Plant Methods, 16(1). https://doi.org/10.1186/s13007-020-00673-7

    2019

    Šantrůček, J., Schreiber, L., Macková, J., Vráblová, M., Květoň, J., Macek, P., & Neuwirthová, J. (2019). Partitioning of mesophyll conductance for CO2 into intercellular and cellular components using carbon isotope composition of cuticles from opposite leaf sides. Photosynthesis Research, 141, 33-51. https://doi.org/10.1007/s11120-019-00628-7

    Májeková, M., Martínková, J., Hájek, T., & Niu, S. (2019). Grassland plants show no relationship between leaf drought tolerance and soil moisture affinity, but rapidly adjust to changes in soil moisture. Functional Ecology, 33(5), 774-785. https://doi.org/10.1111/1365-2435.13312

    Vondrak, J., Urbanavichus, G., Palice, Z., Malicek, J., Urbanavichene, I., Kubásek, J., & Ellis, C. (2019). The epiphytic lichen biota of Caucasian virgin forests: a comparator for European conservation. Biodiversity and Conservation, 28(12), 3257–3276. https://doi.org/10.1007/s10531-019-01818-4

    Vondrak, J., Frolov, I., Davydov, E. A., Yakovchenko, L., Malicek, J., Svoboda, S., & Kubásek, J. (2019). The lichen family Teloschistaceae in the Altai-Sayan region (Central Asia). Phytotaxa, 396(1), 1-+. https://doi.org/10.11646/phytotaxa.396.1.1

    2018

    Plavcová, L., Hronková, M., Šimková, M., Květoň, J., Vráblová, M., Kubásek, J., & Šantrůček, J. (2018) Seasonal variation of d18O and d2H in leaf water of Fagus sylvatica L. and related water compartments. Journal of Plant Physiology, 227, 56-65. https://doi.org/10.1016/j.jplph 2018.03.009

    Vráblová, M., Hronková, M., Vrábl, D., Kubásek, J., & Šantrůček, J. (2018). Light intensity-regulated stomatal development in three generations of Lepidium sativum. Environmental and Experimental Botany, 156: 316-324, 2018. https://doi.org/10.1016/j.envexpbot.2018.09.012

    Světlíková, P., Hájek, T., & Těšitel, J. (2018). Water-stress physiology of Rhinanthus alectorolophus, a root-hemiparasitic plant. PLOS ONE, 13(8), e0200927. https://doi.org/10.1371/journal.pone.0200927

    Světlíková, P., Hájek, T., & Těšitel, J. (2018). A hemiparasite in the forest understorey: photosynthetic performance and carbon balance of Melampyrum pratense. Plant Biology, 20(1), 50-58. https://doi.org/10.1111/plb.12638

    Bengtsson, F., Rydin, H., & Hájek, T. (2018). Biochemical determinants of litter quality in 15 species of Sphagnum. Plant and Soil, 425(1-2), 161-176. https://doi.org/10.1007/s11104-018-3579-8

    Bjorkman, A. D., Myers‐Smith, I. H., Elmendorf, S. C., Normand, S., Thomas, H. J. D., …Hájek, T. et al. (2018). Tundra Trait Team: A database of plant traits spanning the tundra biome. Global Ecology and Biogeography, 27(12), 1402-1411. https://doi.org/10.1111/geb.12821

    Juřicková, L., Pokorný, P., Hošek, J., Horáčková, J., Květoň, J.Zahajská, P., Jansová, A., Ložek, V. (2018). Early postglacial recolonisation, refugial dynamics and the origin of a major biodiversity hotspot. A case study from the Mala Fatra mountains, Western Carpathians, Slovakia. Holocene, 28(4), 583-594. https://doi.org/10.1177/0959683617735592

    2017

    Stolárik, T., Hedtke, B., Šantrůček, J., Ilík, P., Grimm, B., & Pavlovič, A. (2017). Transcriptional and post-transcriptional control of chlorophyll biosynthesis by dark-operative protochlorophyllide oxidoreductase in Norway spruce. Photosynthesis Research, 132, 165-179. https://doi.org/10.1007/s11120-017-0354-2

    Vráblová, M., Vrábl, D., Hronková, M., Kubásek, J., & Šantrůček, J. (2017). Stomatal function, density and pattern, and CO2 assimilation in Arabidopsis thaliana tmm1 and sdd1-1 mutants. Plant Biology, 19, 689-701. https://doi.org/10.1111/plb.12577

    Korrensalo, A., Alekseychik, P., Hájek, T., Rinne, J., Vesala, T., Mehtätalo, L., Mammarella, I., & Tuittila, E. -S. (2017). Species-specific temporal variation in photosynthesis as a moderator of peatland carbon sequestration. Biogeosciences, 14(2), 257-269. https://doi.org/10.5194/bg-14-257-2017

    Vicherová, E., Hájek, M., Šmilauer, P., & Hájek, T. (2017). Sphagnum establishment in alkaline fens: Importance of weather and water chemistry. Science of The Total Environment, 580, 1429-1438. https://doi.org/10.1016/j.scitotenv.2016.12.109

    2016

    Šantrůčková, H., Kubešová, J., Šantrůček, J., Kaštovská, E., & Rejmánková, E. (2016). The effect of P enrichment on exudate quantity and bioavailability - a comparison of two macrophyte species. Wetlands, 36, 789-798. https://doi.org/10.1093/jxb/erv233

    Čada, V., Šantrůčková, H., Šantrůček, J., Kubištová, L., Seedre, M., & Svoboda, M. (2016). Complex physiological response of Norway spruce to atmospheric pollution – decreased carbon isotope discrimination and unchanged tree biomass increment. Frontiers in Plant Science, 7(805). https://doi.org/10.3389/fpls.2016.00805

    Risi, C., Ogée, J., Bony, S., Bariac, T., Raz-Yaseef, N., Wingate, L., Welker, J., Knohl, A., Kurz-Besson, C., Leclerc, M., Zhang, G., Buchmann, N., Santrucek, J., Hronkova, M., David, T., Peylin, P., & Guglielmo, F. (2016). The Water Isotopic Version of the Land-Surface Model ORCHIDEE: Implementation, Evaluation, Sensitivity to Hydrological Parameters. Hydrology Current Research 7, 1-11. https://doi.org/10.4172/2157-7587.1000258

    Skalák, J., Cerný, M., Jedelský, P., Dobrá, J., Ge, E., Novák, J., Hronková, M., Dobrev, P., Vanková, R., & Brzobohatý, B. (2016). Stimulation of ipt overexpression as a tool to elucidate the role of cytokinins in high temperature responses of Arabidopsis thaliana. Journal of Experimental Botany, 67(9). https://doi.org/10.1093/jxb/erw129

    Pichrtová, M., Arc, E., Stöggl, W., Kranner, I., Hájek, T., Hackl, H., Holzinger, A., & Elster, J. (2016). Formation of lipid bodies and changes in fatty acid composition upon pre-akinete formation in Arctic and Antarctic Zygnema (Zygnematophyceae, Streptophyta) strains. FEMS Microbiology Ecology, 92(7), fiw096. https://doi.org/10.1093/femsec/fiw096

    Pichrtová, M., Hájek, T., & Elster, J. (2016). Annual development of mat-forming conjugating green algae Zygnema spp. in hydro-terrestrial habitats in the Arctic. Polar Biology, 39(9), 1653-1662. https://doi.org/10.1007/s00300-016-1889-y

    Plesková, Z., Jiroušek, M., Peterka, T., Hájek, T., Dítě, D., Hájková, P., Navrátilová, J., Šímová, A., Syrovátka, V., Hájek, M., & Wildi, O. (2016). Testing inter‐regional variation in pH niches of fen mosses. Journal of Vegetation Science, 27(2), 352-364. https://doi.org/10.1111/jvs.12348

    Korrensalo, A., Hájek, T., Vesala, T., Mehtätalo, L., & Tuittila, E. -S. (2016). Variation in photosynthetic properties among bog plants. Botany, 94(12), 1127-1139. https://doi.org/10.1139/cjb-2016-0117

    Kubásek, J. (2016). Optical Spectroscopy for Analysis of the Ratio of Stable Isotopes. Competition or Alternative for Conventional Mass Spectroscopy of Stable Isotopes (IRMS)? Chemické listy, 110(3), 166–173.

    2015

    Hronková, M., Wiesnerová, D., Šimková, M., Skůpa, P., Dewitte, W., Vráblová, M., Zažímalová, E., & Šantrůček, J. (2015). Light induced STOMAGEN-mediated stomatal development in Arabidopsis leaves. Journal of Experimental Botany, 66, 4621-4630. https://doi.org/10.1093/jxb/erv233

    Světlíková, P., Hájek, T., & Těšitel, J. (2015). Hydathode trichomes actively secreting water from leaves play a key role in the physiology and evolution of root-parasitic rhinanthoid Orobanchaceae. Annals of Botany, 116(1), 61-68. https://doi.org/10.1093/aob/mcv065

    Vicherová, E., Hájek, M., & Hájek, T. (2015). Calcium intolerance of fen mosses: Physiological evidence, effects of nutrient availability and successional drivers. Perspectives in Plant Ecology, Evolution and Systematics, 17(5), 347-359. https://doi.org/10.1016/j.ppees.2015.06.005

    Hájek, M., Jiroušek, M., Navrátilová, J., Horodyská, E., Peterka, T., Plesková, Z., Navrátil, J., Hájková, P., & Hájek, T. (2015). Changes in the moss layer of Czech fens indicate early succession triggered by nutrient enrichment. Preslia, 87(2), 279-301.

    Mikulášková, E., Hájek, M., Veleba, A., Johnson, M. G., Hájek, T., & Shaw, J. A. (2015). Local adaptations in bryophytes revisited: the genetic structure of the calcium‐tolerant peatmoss Sphagnum warnstorfii along geographic and pH gradients. Ecology and Evolution, 5(1), 229-242. https://doi.org/10.1002/ece3.1351

    Tazoe, Y., Santrucek, J. (2015). Superimposed behavior of gm under ABA-induced stomata closing and low CO2. Plant, Cell and Environment, 38, 385-387. https://doi.org/10.1111/pce.12437


    Click here to view the publications for the previous calendar year exported from the university database

  • Know-how

  • Collaborations

    Vědeckou aktivitu rozvíjíme ve spolupráci s:

    Institute of Plant Moleculat Biology of the CAS in České Budějovice
    Institute of Microbiology of the CAS in Třeboň
    Institute for Cellular and Molecular Botany (IZMB) University of Bonn
    Institute of Experimental Botany of the CAS (transcriptomics, phytohormones, phytopathology)
    AG Ecophysiology for Plants, TUM Munich, Germany (stable isotopes)
    University of Chemistry and Technology, Prague (Plant biochemistry, liposomes)
    Institute of Genetics, LMU Munich (interaction of plants with microorganisms)

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D123 - on specifying the conditions for the study of citizens from sanctioned countries

Provision of the Dean D 123
on specifying the conditions for the study of citizens from sanctioned countries

on 1. August 2023

Studies at the Faculty of Science are generally governed by Act No. 111/1998 Coll., This Measure specifies the conditions of study for citizens of countries against which national or international sanctions involving technical assistance and intangible technology transfer are applied. According to the European Commission Opinion C(2019/5883) of 5 August 2019, technical assistance includes the provision of education.

Article 1. List of countries whose nationals are covered by this Measure

The list of sanctioned countries is set out in Annex 1 to this Measure. This list shall be drawn up and updated on the basis of the provisions currently in force and shall be reviewed at least once a year.

Article 2. Enrolment of individual subjects

A student who is a national of a country listed in Annex 1 to this Measure may be de-enrolled in a course identified as at-risk or prevented from enrolling in such a course. In the event of cancellation of enrolment in a course, the student will be notified in writing by a message sent to the school email.

Article 3. Theses assignment

A student who is a national of a country listed in Annex 1 to this Measure may only be assigned a qualifying thesis that is purely basic research and will be published in full immediately after submission for defence. Publication shall be arranged by the study department, unless the student himself/herself has set it when submitting the thesis. The student, the thesis supervisor and any external partner must sign an informed consent to the immediate full publication of the work after submission for defence before the submission of the thesis or dissertation, i.e. the submission of the assignment protocol. In the case of dissertations, the informed consent is signed during the admission procedure and forms part of the documentation for the decision on the outcome of the procedure. The informed consent form is attached as Annex 2 to this Measure.

Article 4. Collaboration on research projects

A student who is a national of a country listed in Annex 1 to this measure may not be part of a research team conducting applied research or basic research for which rapid commercialisation can reasonably be expected.

Article 5. Closing remarks

  1. This measure shall enter into force on the date of its issue.
  2. Theses commissioned before this measure is issued is not affected, but supervisors are requested to apply the measure as far as possible.

 

In České Budějovice, on 1. August 2023

prof. RNDr. František Vácha, Ph.D.
dean PřF JU

Read more …D123 - on specifying the conditions for the study of citizens from sanctioned countries

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Lenka Gahurová

Mgr. Lenka Gahurová, Ph.D. (née Veselovská)

head of the Developmental Epigenetics and Bioinformatics Laboratory

Faculty of Science, University of South Bohemia
Branišovská 31, 37005 České Budějovice
building B, ground floor, door 181
 
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Tel. +420 389 032 275


Mgr. Lenka Gahurová, Ph.D. (née Veselovská)

Current possition

Assistant professor and group leader since 2023

Developmental Epigenetics and Bioinformatics Laboratory, Department of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic

Previous possitions

postdoctoral research fellow 5/2015 – 12/2022

 Laboratory of Early Mammalian Development, Department of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic

research scientist and bioinformatician (part-time) 2/2017 – 12/2022

Laboratory of Biochemistry and Molecular Biology of Germ Cells, Institute of Animal Physiology and Genetics CAS, v.v.i, Libechov, Czech Republic

bioinformatician (part-time) 10/2020 – 12/2022

Laboratory of Chemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry CA, v.v.i, Prague, Czech Republic

Education

Ph.D. in Developmental Epigenetics 2011 - 2015

Epigenetics Programme, Babraham Institute, University of Cambridge, Cambridge, United Kingdom, supervisor: Dr. Gavin Kelsey

MSc. in Genetics 2009 – 2011

Molecular Biology and Virology, Faculty of Science, Charles University, Prague, Czech Republic, supervisor: Prof. Ilona Hromadníková

visiting MSc. student of Genetics Part II Programme 2009 – 2010

Department of Genetics, Cambridge University, Cambridge, United Kingdom including 11 months research project at Cambridge Institute for Medical Research, Cambridge University, Cambridge, United Kingdom, supervisor Dr. Lucy Raymond

BSc. in Biology 2006-2009

Faculty of Science, Charles University, Prague, Czech Republic

Competitive fellowships and scholarships awarded

TUBITAK 12/2022

The scientific and technological research council of Turkiye) short-term visiting fellowship (travel and personal costs associated with academic visit)

Pamětný grant Martiny Roeselové 11/2021

1 of 4 awards for excellent young scientists with children under age of 6

Marie Sklodowska-Curie Actions Individual Fellowship 6/2017-7/2021

24 months (suspended for total 26 months for 2 maternity leaves)

University of South Bohemia postdoctoral fellowship 2006-2009

1 award per year in Natural Sciences (salary only)

Keystone Symposia The Future of Science Fund Scholarship 1/2014

1 of 4 awards selected from abstracts, for participation at the Keystone Symposium on Epigenetic Programming and Inheritance, Boston, US

Babraham Institute and University of Cambridge European Ph.D. scholarship 10/2011-9/2014

1 of 3 awards, full university fees and living costs for 36 months

Read more …Lenka Gahurová

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Developmental Epigenetics and Bioinformatics Laboratory

Developmental Epigenetics and Bioinformatics Laboratory

The laboratory was founded in 2023. We study unconventional mammalian model species to understand evolutionary history and molecular (especially epigenetic) mechanisms of long-term female fertility at the levels of oocytes, their ovarian niche, and successful embryonic development.

Lab members

  • Lenka Gahurová

    head of the laboratory

  • Eva Kopecká

    technical assistant, researcher

  • Nikolas Tolar

    Ph.D. candidate

  • Minh Triet Le

    Ph.D. candidate

  • Alyssa Malapit Fontanilla

    Ph.D. candidate

  • Eliška Bláhová

    MSc. student

  • Jakub Kořenář

    MSc. student

  • Michaela Kazíková

    BSc. student

  • Pavlína Chudá

    BSc. student

  • Lenka Ošmerová

    BSc. student

  • Anja Drobnjak

    BSc. student

  • Vilja Langer

    BSc. student

  • Laura Andessner-Angleitner

    BSc. student

Research

Mammalian oocytes (=female eggs) are established during female embryonic development as a finite pool. They are essential for propagation of the species yet are among the oldest cells in the body – they can be several decades old in long-lived species such as humans. They preserve their quality for extraordinarily long time compared to most other cell types in the body, nevertheless, female fertility is one of the first physiological functions undergoing age-associated decline. This decline is generally associated with decreased quantity and quality of oocytes, affecting the ability to sustain successful embryonic development.
Studies on female fertility and oocyte biology are mostly performed on mouse, a classical mammalian model. However, mice are fertile only for <12 months, and cannot therefore fully recapitulate biological processes in long-lived species that are fertile for several decades. Moreover, increasing number of studies show that mechanism uncovered in mouse do not universally apply across mammals.

 

What we ask:
(1) What are the molecular mechanisms conferring long-term oocyte quality and what can go wrong? How is oocyte quality and quantity affected by their ovarian niche and physiological processing taking place in the ovary (such as ovulations)?
(2) How does the dynamic relationship between host and transposons affect oocyte biology, maternal to zygotic transition, and embryonic development, and does it change during maternal aging?


What we do:
We employ various sequencing (genomics, transcriptomics, epigenomics) and imaging approaches to study oocytes, ovaries and embryos of multiple short-lived and long-lived rodent species from different phylogenetic groups – especially naked mole-rat, giant mole-rat, guinea pig, coruro, blind mole rat and mouse.

Read more …Developmental Epigenetics and Bioinformatics Laboratory

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CV Fencková

Mgr. Michaela Fencková, Ph.D.

head of the Laboratory of Neurogenetics

Faculty of Science, University of South Bohemia
Branišovská 31, 37005 České Budějovice
building B, ground floor, door number 194b
 
Email: fenckm00@prf.jcu.cz
Tel. +420 387772227


Mgr. Michaela Fencková, Ph.D.

Current possitions

Group leader since 2022

Laboratory of Neurogenetics

Assistant Professor since 2021

Department of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia, Ceske Budejovice, Czechia 

Previous possitions

Postdoctoral fellow 2017 – 2021

Department of Human Genetics, Radboud University Medical Centre, The Netherlands

Postdoctoral fellow 2016 – 2017

School of Life Sciences, University of Dundee, UK

Postdoctoral fellow 2011 – 2016

Department of Human Genetics, Radboud University Medical Centre, The Netherlands

Education

PhD, Molecular and Developmental Biology and Genetics 2012

Faculty of Science, University of South Bohemia, Czechia. The role of adenosine in Drosophila stress response”  supervisor: Tomáš Doležal

MSc., Experimental Biology 2016 – 2017

Faculty of Science, University of South Bohemia, Czechia

BSc., Biology 2003

Faculty of Science, University of South Bohemia, Czechia

Awards, grants and memberships

Member of Committee for Higher Education and Training (CHET) of the Federation of European Neuroscience Societies (FENS) 2024 - 2026 Read more
FENS-Kavli Network of Excellence 2023 - 2027

(2023-2025, elected vice-chair)

Read more
L'Oreal For Women in Science Award 2023 Read more
EMBO Installation Grant 2023 - 2027 Read more
ERC-CZ grant 2023 - 2025

“Opening novel avenues in research of neurodevelopmental disorders”

Czech Science Foundation grant 2023 - 2025

“Drosophila habituation to close the gap in genetic diagnostics of neurodevelopmental disorders”

News and media

  • Michaela Fencková became a member of the prestigious multidisciplinary international network of scientists FKNE

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  • Dr Fenckova from FSC USB has joined the prestigious multidisciplinary international network of FKNE scientists

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  • Michaela Fencková has won the L´Oreal Women in Science Award for her work on fruit flies

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  • Article in MF DNES (in Czech)

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  • The Faculty of Science of the University of South Bohemia has received a prestigious international EMBO grant (in Czech)

    Read more

  • Understanding the power of habits

    Read more

  • EMBO Installation Grants: 11 winners announced

    Read more

Read more …CV Fencková

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