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PRF

Infection Biology and Immunology

Infection Biology and Immunology

Coordinator:
RNDr. Jindřich Chmelař, Ph.D. (PřF JU)
Selection of our students' publications:

RNDr. Jindřich Chmelař, Ph.D. - Laboratory of Vector-Host Interaction
prof. RNDr. Jan Kopecký, CSc. - Laboratory of Molecular Immunology
RNDr. Jan Ženka, CSc. - Laboratory of Cancer Immunotherapy
Mgr. Jaroslava Lieskovská, Ph.D.
RNDr. Ján Štěrba, Ph.D. - Laboratory of Applied Biochemistry
doc. RNDr. Daniel Růžek, Ph.D. - Laboratory of Arbovirology
prof. RNDr. Libor Grubhoffer, CSc. - Laboratory of Molecular Ecology of Vectors and Pathogens
MVDr. Kateřina Jirků-Pomajbíková, Ph.D. - Laboratory of parasitic therapy

Selection of our students' publications:

  • Kotál J, Stergiou N, Buša M, Chlastáková A, Beránková Z, Řezáčová P, Langhansová H, Schwarz A, Calvo E, Kopecký J, Mareš M, Schmitt E, Chmelař J, Kotsyfakis M. The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin. Cellular and Molecular Life Sciences. 76, 2003–2013 (2019). DOI: https://doi.org/10.1007/s00018-019-03034-3
  • Selinger M, Tykalová H, Štěrba J, Věchtová P, Vavrušková Z, Lieskovská J, Kohl A, Schnettler E, Grubhoffer L. (2019) Tick-borne encephalitis virus inhibits rRNA synthesis and host protein production in human cells of neural origin. Plos Neglected Tropical Diseases 13(9): e0007745. DOI: https://doi.org/10.1371/journal.pntd.0007745
  • Caisová V, Uher O, Nedbalová P, Jochmanová I, Kvardová K, Masáková K, Krejčová G, Paďouková L, Chmelař J, Kopecký J, Ženka J. Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis. International Immunopharmacology 2018 Jun;59:86-96. doi: 1016/j.intimp.2018.03.038

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Molecular Biology and Physiology of Plants

Molecular Biology and Plant Physiology

Coordinator:
prof. Ing. Jiří Šantrůček, CSc. (Přf JU)
Scientific groups and supervisors:

prof. Ing. Jiří Šantrůček, CSc. – Stable isotopes in photosynthesis
Ing. Martin Janda, Ph.D. - Molecular plant-microbe interactions
RNDr. Tomáš Hájek, Ph.D.
Mgr. Iva Mozgová, Ph.D. – Plant epigenetics
doc. MSc. Michael Alois Wrzaczek, PhD. - Plant Molecular Signalling
prof. Hendrik Küpper, Ph.D. - Plant Biophysics and Biochemistry
doc. Ing. Roman Sobotka, Ph.D. – Laboratory of photosynthetic pigments
prof. RNDr. Josef Komenda, CSc., DSc. – Biogenesis of Photosystem II
prof. RNDr. Ondřej Prášil, Ph.D. - Ecophysiology of algae
RNDr. Pavel Hrouzek, Ph.D. - Bioactive compounds from Cyanobacteria

Selection of our students' publications:

  • Pazderník, M, Mareš, J, Pilný, J, Sobotka, R: The antenna-like domain of the cyanobacterial ferrochelatase can bind chlorophyll and carotenoids in an energy-dissipative configuration. Journal of Biological Chemistry 294(29), 11131-11143, 2019. DOI:https://doi.org/10.1074/jbc.RA119.008434
  • Bučinská, L, Kiss, É, Koník, P, Knoppová, J, Komenda, J, Sobotka, R: The Ribosome-Bound Protein Pam68 Promotes Insertion of Chlorophyll into the CP47 Subunit of Photosystem II. Plant Physiology 176(4), 2931-2942, 2018. DOI: https://doi.org/10.1104/pp.18.00061
  • Bečková, M, Gardian, Z, Yu, J, Konik, P, Nixon, PJ, Komenda, J: Association of Psb28 and Psb27 Proteins with PSII-PSI Supercomplexes upon Exposure of Synechocystis sp. PCC 6803 to High Light. Molecular Plant 10(1), 62-72, 2017. DOI: https://doi.org/10.1016/j.molp.2016.08.001

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Physiology and Developmental Biology of Animals

Physiology and Developmental Biology of Animals

Coordinator:
prof. RNDr. Dalibor Kodrík, CSc. (ENTÚ BC AV ČR) / doc. Alexander W. Bruce, Ph.D.
 Scientific groups and supervisors:

doc. Alexander W. Bruce, Ph.D. - Laboratory of Early Mammalian Developmental Biology
doc. Mgr. Tomáš Doležal, Ph.D. - Laboratory of Molecular Integrative Physiology in Drosophila
Mgr. Adam Bajgar, Ph.D. - Dmel macrophages squad
prof. RNDr. Dalibor Kodrík, CSc. - Laboratory of Insect Physiology
prof. RNDr. Marek Jindra, CSc. - Laboratory of Developmental Genetics
Mgr. David Doležel, Ph.D. - Laboratory of Molecular Chronobiology
prof. Ing. Vladimír Košťál, CSc. - Laboratory of Insect Diapause
prof. RNDr. Michal Žurovec, CSc. - Laboratory of Molecular Genetics

Selection of our students' publications:

  • Kaniewska M., Vaněčková H., Doležel D., Kotwica-Rolinska J. (2020) Light and temperature synchronizes locomotor activity in the linden bug, Pyrrhocoris apterus. Frontiers in Physiology 11: DOI: 10.3389/fphys.2020.00242
  • Kotwica-Rolinska J., Chodáková L., Chvalová D., Krištofová L., Fenclová I., Provazník J., Wu C., Bertolutti M., Doležel D. (2019) CRISPR/Cas9 genome editing introduction and optimization in the non-model insect Pyrrhocoris apterus. Frontiers in Physiology 10: DOI: 10.3389/fphys.2019.00891
  • Lin Y.-H., Maaroufi H., Ibrahim E. A. S., Kučerová L., Žurovec M. (2019) Expression of human mutant huntingtin protein in Drosophila hemocytes impairs immune responses. Frontiers in Immunology 10: DOI: 10.3389/fimmu.2019.02405

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Evolutionary Molecular Biology and Genetics

Evolutionary Molecular Biology and Genetics

Coordinator:
RNDr. Petr Nguyen, Ph.D. (Přf JU)
Scientific groups and supervisors:

RNDr. Petr Nguyen, Ph.D. - Laboratory of Chromosomics
RNDr. Magda Zrzavá, Ph.D. - Laboratory of Molecular Cytogenetics
doc. RNDr. Eva Nováková, Ph.D. - Arthropods, symbionts, microbiomes
prof. RNDr. František Marec, CSc. -  Laboratory of Molecular Cytogenetics
RNDr. Jiří Macas, Ph.D. – Laboratory of Molecular Cytogenetics
prof. Ing. Miroslav Oborník, Ph.D. - Laboratory of Evolutionary Protistology
Mgr. Aleš Horák, Ph.D. - Laboratory of environmental genomics
doc. RNDr. Jan Štefka, Ph.D. -  Laboratory of Molecular Ecology and Evolution
Mgr. Martin Kolísko, Ph.D. - Laboratory of Genomics and Diversity of Protists

Selection of our students' publications:

  • Avila Robledillo, L., Neumann, P., Koblizkova, A., Novak, P., Vrbova, I., Macas, J. (2020) – Extraordinary sequence diversity and promiscuity of centromeric satellites in the legume tribe Fabeae. Molecular Biology and Evolution. 37:2341-2356. doi.org/10.1093/molbev/msaa090
  • Vondrak, T., Avila Robledillo, L., Novak, P., Koblizkova, A., Neumann, P., Macas, J. (2020) – Characterization of repeat arrays in ultra-long nanopore reads reveals frequent origin of satellite DNA from retrotransposon-derived tandem repeats. The Plant Journal. 101:484-500. doi.org/10.1111/tpj.14546
  • Flegontova O., Flegontov P., Malviya S., Audic S., Wincker P., de Vargas C., Bowler C., Lukeš J., Horák A. (2016) Extreme diversity of diplonemid eukaryotes in the ocean Current Biology 26: 3060-3065. DOI: 10.1016/j.cub.2016.09.031

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Molecular and Cell Biology

Molecular and Cell Biology

Coordinator:
doc. Hassan Hashimi, Ph.D. (PARÚ BC AV ČR)
Scientific groups and supervisors:

doc. Mgr. Tomáš Doležal, Ph.D. - Laboratory of Molecular Integrative Physiology in Drosophila
Mgr. Adam Bajgar, Ph.D. - Dmel macrophages squad
RNDr. Alena Krejčí Bruce, Ph.D. - Laboratory of Bee Biology
prof. RNDr. Julius Lukeš, CSc. - Laboratory of Molecular Biology of Protists
doc. Hassan Hashimi, Ph.D. - Laboratory of Molecular Biology of Protists
RNDr. Alena Panicucci Zíková, Ph.D. - Laboratory of Functional Biology of Protists
RNDr. Zdeněk Paris, Ph.D. - Laboratory of RNA Biology of Protists
RNDr. Petr Kopáček, CSc. - Laboratory of Vector Immunology
RNDr. Daniel Sojka, Ph.D. - Laboratory of Vector Immunology
RNDr. Radek Šíma, Ph.D. - Laboratory of Vector Immunology
Dr. Astrid Holzer, Ph.D. - Laboratory of Fish Protistology
prof. RNDr. Michal Žurovec, CSc. - Laboratory of Molecular Genetics
RNDr. Radmila Čapková Frydrychová, Ph.D. - Laboratory of Telomere Research
RNDr. Zdeněk Franta, Ph.D. – Makrokomplex

Selection of our students' publications:

  • Nenarokova A., Záhonová K., Krasilnikova M., Gahura O., McCulloch R., Zíková A., Yurchenko V., Lukeš J. (2019) Causes and effects of loss of classical nonhomologous end joining pathway in parasitic eukaryotes mBio 10: e01541-19. DOI: 10.1128/mBio.01541-19
  • Krejcova G, Danielova A, Nedbalova P, Kazek M, Strych L, Chawla G, Tennessen JM, Lieskovská J, Jindra M, Dolezal T, Bajgar A (2019) Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense. eLife 14;8. pii: e50414. doi: 10.7554/eLife.50414. 
  • Kaurov I, Vancová M, Schimanski B, Cadena LR, Heller J, Bílý T, Potěšil D, Eichenberger C, Bruce H, Oeljeklaus S, Warscheid B, Zdráhal Z, Schneider A, Lukeš J, Hashimi H. The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import. Current Biology. 2018 Nov 5;28(21):3393-3407.e5. doi: 10.1016/j.cub.2018.09.008.

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